Aptalis Pharmaceutical Technologies
100 Somerset Corporate Boulevard
Aptalis is a wholly owned subsidiary of Forest Laboratories (NASDAQ: FRX) focused on improving health and quality of care by providing specialty therapies for patients around the world. Our pipeline of innovative, effective therapies for unmet medical needs is robust, including specialty pharmaceutical products for patients suffering from cystic fibrosis and gastrointestinal disorders.
Aptalis Pharmaceutical Technologies develops and manufactures enhanced pharmaceutical products based on its broad range of proprietary oral drug delivery technologies, including taste masking, bioavailability enhancement, and customized drug release. We utilize these technologies to develop novel prescription and OTC products that have advantages over existing products and address unmet medical needs. Our integrated R&D and manufacturing teams in the U.S. and Europe work with our partners from formulation through scale-up and commercial-scale manufacturing. Our track record of success includes over 40 products that are commercialized around the world by our partners. To learn more visit: www.AptalisPharmaceuticalTechnologies.com.
Aptalis Pharmaceutical Technologies is focused on developing high-value products with robust, defensible proprietary positions that grow the commercial value of our partners' portfolios. We have a variety of products available for licensing across multiple therapeutic categories and collaborate with our partners to develop customized, value-added Rx and OTC products. Key products available for out-licensing are:
Ondansetron ER is the first once-a-day formulation of the leading US oral 5-HT3 anti-emetic that provides therapeutic improvement over current treatments. 5-HT3 category prescriptions have a combined annual growth rate (CAGR) of 41%.
• Patient benefits: Single dose formulation is designed to minimize side effects of therapy and promote patient adherence, improving treatment results, and to reduce emesis-related patient anxiety, a risk factor for radiation-induced nausea and vomiting (RINV)
• Clinician benefits: Ondansetron ER is designed to provide therapeutic improvement over current treatments as identified by clinicians in market research
AdvaTab® Paracetamol (Acetaminophen) orally disintegrating tablet (ODT)
Launch-ready and formulated in a range of strengths for adult and pediatric dosing, AdvaTab Acetaminophen is a convenient, patient-friendly OTC pain reliever. AdvaTab Paracetamol (Acetaminophen) ODT is part of a new segment in the in the popular analgesic OTC market in the US and worldwide, by leveraging a successfully formulated and patient-friendly fast dissolving ODT.
Product developed according to European Pharmacopeia (EP) standards, complies with US OTC monograph standards, and is shown to be bioequivalent to the reference product. AdvaTab Acetaminophen ODT can be formulated in a range of dosages (80mg-500mg).
AdvaTab Temazepam ODT
Enhance your pipeline in a growing category with a novel, patient-friendly dosage form of a top-selling sleep aid. AdvaTab Temazepam is the first ODT formulation of a highly prescribed benzodiazepine. AdvaTab Temazepam is formulated in a convenient patient-friendly dosage form, potentially creating a new segment for the growing Rx sleep-aid market.
• 8.4 million US Temazepam prescriptions annually (IMS 2009-2010)
• 5% category compound annual growth rate (CAGR)
AdvaTab Hydrocodone / Acetaminophen ODT
The proprietary ODT formulation of Hydrocodone / Acetaminophen creates the opportunity for a partner to grow a new segment of the growing Rx pain market with the first and only ODT formulation of the most-prescribed drug combination in the US.*
As the first ODT formulation of the most-prescribed drug combination in the US (120 million prescriptions annually**), AdvaTab Hydrocodone / Acetaminophen fast dissolving ODT creates a unique market segment for a convenient, patient-friendly dosage form that facilitates accurate dosing and easier administration.
Formulated in two convenient dosage strengths, AdvaTab Hydrocodone / Acetaminophen's formulation and manufacturing processes are scalable achieve multiple dosage strengths.
*Based on information currently available in the public domain
Our owned and in-licensed patent portfolio consists of over 900 granted patents and pending applications.
This portfolio is composed of patents with claims directed to our formulation technologies and related materials, processes, equipment and methods of manufacture. We also have many product-related patents, which contain more specific claims directed to particular drugs or classes of drugs in combination with our formulation technology.
Aptalis Pharmaceutical Technologies endeavors to offer the most effective patent protection possible to our partners based on our broad and diversified portfolio of Pharmaceutical Technologies.
Aptalis Pharmaceutical Technologies