Phase II
BioSpace takes a quick look at some of the news coming from biotech and pharma companies from across Europe and Asia.
In an announcement short on details and trying to put a positive spin on things, San Diego-based Conatus Pharmaceuticals indicated its emricasan failed its Phase IIb ENCORE-NF clinical trial in patients with NASH.
Independent data monitoring committee advises aducanumab unlikely to meet primary endpoints, leading to decision to discontinue the trials
Perhaps the last big hope for a successful Alzheimer’s drug just died. Biogen and its collaboration partner, Eisai, announced they were discontinuing the global Phase III clinical trials of aducanumab in patients with mild cognitive impairment from Alzheimer’s.
MorphoSys AG andI-Mab Biopharma announced that the first patient has been dosed in a phase 2 clinical study in Taiwan to evaluate MorphoSys’s investigational human CD38 antibody TJ202/MOR202 in patients with relapsed or refractory multiple myeloma.
Only a few months after GlaxoSmithKline acquired Waltham, Mass.-based Tesaro, Tesaro released promising data from its Phase I/II GARNET study of dostarlimab in endometrial cancer.
Sterna biologicals GmbH & Co. KG announced that the company held a Scientific Advisory Board meeting to evaluate the phase IIb clinical development program for SB012 in ulcerative colitis.
TLC announced that the first patient has been dosed a Phase II clinical trial for TLC590 following bunionectomy.
Aerpio said the Phase IIb asset did show some positive data in a number of pre-specified secondary endpoints, including changes in Urine Albumin-Creatinine Ratio, a measure of kidney function, and in intraocular pressure.
The stock is up more than 100 percent after the company announced positive results from a Phase IIb study of lebrikizumab, an investigational therapy, in adult patients with moderate-to-severe atopic dermatitis.
PRESS RELEASES