Chief Technology Officer, Terray Therapeutics
Narbe is the Chief Technology Officer at Terray Therapeutics, where over the last six years, he has built the AI and data backbone for EMMI, Terray’s integrated experimentation and chemistry-first AI platform for novel drug discovery and development. EMMI powers Terray’s internal immunology pipeline and partnered work with BMS and Gilead, as well as co-development work with Odyssey Therapeutics.
From processing the data produced by Terray’s experimental platforms to developing predictive and generative AI models, his team has developed the infrastructure that complements and powers Terray’s tightly integrated lab-in-the-loop small-molecule design and development process. He has assembled a diverse team of experts – from data scientists to machine learning researchers to medicinal chemists who work directly on molecule and model development.
Under his leadership, the EMMI platform has generated more than 20 billion experimentally derived binding measurements – a growing dataset that surpasses all publicly available data combined by more than 60-fold, accelerating hit identification and powering the entire drug discovery process at Terray.
Prior to joining Terray in 2020, Narbe was a Senior Scientist at Amgen, responsible for supporting all aspects of computational small-molecule drug discovery, including the development of advanced quantum mechanics and machine learning methods. While at Amgen, Narbe contributed to the development of AMG 193, an MTA-cooperative PRMT5 inhibitor evaluated in clinical trials for MTAP-deleted solid tumors. He is also the developer of ωB97M-V, widely regarded as one of the most accurate density functionals in quantum chemistry and extensively used by leading AI research organizations as the ground-truth benchmark for training machine learning interatomic potentials. Narbe received a B.S. in Chemical Engineering and a Ph.D. in Quantum Chemistry from UC Berkeley, and was a postdoc in Chemical Physics at Caltech. His publications have been cited over 15,000 times. He lives with his family in Southern California.
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