Nurix Inc.

1700 Owens Street
Suite 205
San Francisco
United States

Tel: 415-660-5320


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About Nurix Inc.

Nurix is a science-focused company that is committed to bringing novel, first-in-class therapies to patients. Nurix is a leader in discovering a new class of drugs that work by modulating E3 ligases within the ubiquitin proteasome system (UPS), a regulatory network that controls protein levels within the cell.

Nurix’s scientific team has established an innovative drug discovery platform that can either increase the levels of specific proteins through direct inhibition of ligase function, or eliminate disease proteins by harnessing ligases to ubiquitinate and redirect them to the proteasome for degradation. A key distinction of degrader technology over classical small molecule inhibition is that it has the potential to target proteins previously considered ‘undruggable’. Nurix was founded by internationally recognized experts in the UPS field and received its initial funding from leading life science investors, Third Rock Ventures and The Column Group.

In 2019, Nurix entered into a multi-year strategic collaboration with Gilead to discover targeted protein degraders in multiple therapeutic areas. Nurix is based in San Francisco’s biotechnology hub, Mission Bay – where academia and industry come together for cutting-edge life-saving research.


12 jobs with Nurix Inc.