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Associate Scientist, Translational Sciences

Employer
Neogene Therapeutics
Location
Santa Monica, CA
Start date
May 19, 2024

View more

Discipline
Science/R&D, Biotechnology
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Beach, Best Places to Work

Job Details

At AstraZeneca's Oncology R&D division, we follow the science to explore and innovate. We are working towards treating, preventing, modifying, and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference and have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs.

Position Summary

We are seeking an associate scientist with expertise in NGS, molecular biology, and assay development. The position of Associate Scientist, Translational Sciences performs NGS-based assays, sequencing libraries, organizing and analyzing results, and communicating and presenting findings in team meetings. This position is based in Santa Monica, CA and reports to Senior Scientist.

Responsibilities

  • Tissue and primary cell preparation into single cell suspension.
  • Perform bulk and single cell NGS workflows such as 10X immunoprofiling.
  • Conduct Illumina library sequencing.
  • Troubleshoot to optimize assay performance and improve robustness.
  • Work independently and as part of a collaborative team to design, plan, and execute assays to support NGS-based projects.
  • Contribute to data tracking and management using ELN.
  • Meet established timeliness, maintain accurate records of work, and clearly communicate results.
  • Present data within the group and at meetings.
  • Support other responsibilities as required to meet corporate goals.

Education and Experience

  • BS with a minimum of 7+ years of experience, or MS with and 5-7 lab experience, or PhD with 2 years of industry experience.
  • A background in genomics and molecular biology.
  • Hand-on expertise in NGS library preparation.
  • Proficiency in single cell NGS platforms.
  • Experience handling Illumina sequencers.
  • Experience with tissue dissociation and primary cell preparation into single cell suspension.
  • Team-oriented mindset with ability to work independently and collaboratively.
  • Comfortable in a fast-paced company environment and able to adjust workload based upon changing priorities.
  • Self-motivated and willing to accept temporary responsibilities outside of initial job description.
  • Experience in cell culture aseptic techniques.
  • Familiarity with bioinformatic pipelines for analyzing NGS data.
  • Background in human immunology and cancer immunotherapy.

The annual base salary for this position ranges from $105,000 to $124,000. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related experience. If hired, employee will be in an "at-will position" and we reserve the right to modify base salary (and any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Benefits

  • Short-term incentive bonus opportunity
  • Equity-based long-term incentive program
  • 401(k) plan
  • Paid vacation and holidays; paid leaves
  • Health benefits including medical, prescription drug, dental, and vision coverage.

Neogene Therapeutics requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

DE&I Statement

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

Company

Neogene Therapeutics is a global, preclinical stage biotechnology company pioneering the development of next generation, fully individualized engineered T cell therapies for a broad spectrum of cancers.

Our proprietary neoantigen T cell receptor (TCR) discovery and T cell engineering platform identifies TCR genes with specificity for neoantigens – found exclusively on cancer cells as a result of cancer-associated DNA mutations.

Cancer is a genetically individual disease – no two tumors are exactly the same. These variations create neoantigens – unique targets for every tumor. Neogene’s novel approach delivers a tailored T cell therapy containing a unique set of specific TCR genes for each individual patient. Engineered into patient-derived T cells, these TCRs are directed toward neoantigens in tumor cells, with the goal of eliciting strong and durable responses in a variety of solid tumor indications.

We offer the opportunity to join a highly dynamic biotech start-up. You can expect a collaborative environment created by a team with deep scientific expertise and an industrial track-record in T cell therapies. We value pro-active team-players who pursue their goals with dedication, endurance and a daring mindset. If you share our commitment to make a difference to patients in need, we can provide an exciting opportunity for your career.

Company info
Website
Location
2225 Colorado Avenue
Santa Monica
CA
90404
United States

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