Skip to main content

This job has expired

You will need to login before you can apply for a job.

Medical Director - Senior Medical Director, Clinical Development (MD)

Nurix Therapeutics
San Francisco, CA
Start date
May 15, 2024

View more

Clinical, Clinical Development, Clinical Medicine
Required Education
Position Type
Full time
Biotech Bay

Job Details

Medical Director - Sr. Medical Director, Clinical Development (MD)

We are seeking an experienced clinician with strong leadership skills who is driven by science and the desire to develop novel therapies for cancer patients.  The successful candidate will have expertise in the design and conduct of early phase oncology clinical trials and a strong interest in translational medicine.

Reporting to the Head of Clinical Development, the individual will be responsible for the design, implementation, monitoring, data analysis and reporting of clinical studies for Nurix’s oncology portfolio. The individual will also serve as a medical expert resource for drug discovery teams and business development activities.  The role provides an opportunity for leadership growth in a dynamic small company environment.

Specific responsibilities include:

  • Provide strategic input for innovative clinical development plans, incorporating the current therapeutic area landscape
  • Lead the design and implementation of early stage clinical projects, with responsibility for medical aspects of phase 1-2 clinical trials
  • Serve as lead author of clinical documents: protocols, investigator’s brochures, case report form design and data analysis plans
  • Participate/lead the preparation of clinical sections of relevant regulatory filings to Health Authorities
  • Partner closely with the Clinical Operations head in the conduct and execution of Nurix’s clinical trials
  • Serve as Medical Monitor for clinical trials, reviewing safety and efficacy data for routine medical data review, trend review, and safety signals from ongoing trials
  • Support exploratory biomarker efforts to aid clinical and project data-driven decisions
  • Lead medical aspects of investigator and clinical advisory boards
  • Develop and manage relationships with key opinion leaders for clinical programs
  • Represent Nurix at external events, including scientific and medical conferences and business development activities


  • MD with board certification or eligibility in Oncology or Hematology/Oncology
  • 3-5 years of drug development experience in biotechnology or pharmaceutical industry, or a combination of academia and industry
  • Proven experience with clinical trial design, execution, medical monitoring, and reporting of controlled clinical trials in oncology including working with external service providers
  • Experience with design, execution, and analysis of Phase 1-2 clinical oncology studies with small molecule targeted or immunological therapies
  • Demonstrable knowledge of regulatory procedures and guidelines in the US and other geographic regions
  • Understanding of basic science relevant to clinical oncology
  • Ability to work collaboratively in a fast-paced matrix environment
  • Excellent written and oral communication skills

Nurix Therapeutics, Inc. is committed to protecting and respecting your privacy and personal information, including information collected by Nurix when you apply for a job with Nurix or in the course of your employment with Nurix.  By applying for a position at Nurix, you agree to our collection and use of personal information as described in our Privacy Policy ( 


Nurix Therapeutics is a biopharmaceutical company focused on the discovery, development and commercialization of small molecule therapies designed to modulate cellular protein levels as a novel treatment approach for cancer and immune disorders. Leveraging Nurix’s extensive expertise in E3 ligases together with its proprietary DNA-encoded libraries, Nurix has built DELigase, an integrated discovery platform to identify and advance novel drug candidates targeting E3 ligases, a broad class of enzymes that can modulate proteins within the cell. Nurix’s drug discovery approach is to either harness or inhibit the natural function of E3 ligases within the ubiquitin proteasome system to selectively decrease or increase cellular protein levels.

Nurix’s wholly owned pipeline comprises targeted protein degraders of Bruton’s tyrosine kinase, a B-cell signaling protein, and inhibitors of Casitas B-lineage lymphoma proto-oncogene-B, an E3 ligase that regulates T cell activation. Nurix is headquartered in San Francisco, California.

Company info
1700 Owens Street
Suite 205
San Francisco

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert