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Sr. Scientist I

Employer
AnaptysBio, Inc.
Location
San Diego, CA
Start date
May 13, 2024

View more

Discipline
Science/R&D, Biotechnology
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Beach, Best Places to Work

Job Details

Job Type Full-time

Position Summary

This position is involved in the initiation, strategic design, implementation, and execution of antibody-based drug discovery projects in autoimmunity and inflammation. This includes applying advanced scientific principles and concepts in immunology and inflammation to creatively and effectively solve difficult problems and achieve project-related company objectives. The position may identify and develop research opportunities in new areas. 

  

Essential Functions

  • Uses advanced scientific concepts to support projects, solve a wide range of difficult problems using effective and creative approaches to achieve corporate objectives
  • Effectively designs key experiments to support existing projects and new scientific areas and technologies; analyze and      interpret data and prepare associated documentation to support project objectives
  • Initiates and/or co-lead Discovery Projects, including designing and executing key strategies, methodologies or approaches and experiments to further project objectives
  • Works effectively as a member of multi-disciplinary, cross-functional teams to accomplish project goals
  • Contributes to reagent production and validation and the establishment of antibody screening assays to enable the initiation of antibody discovery to new targets
  • Participates in the effective mentoring, supervision, and professional development of junior laboratory staff; oversee/troubleshoot experimental design of supervised laboratory staff
  • Presents research findings clearly and effectively at internal and external meetings
  • Prepares internal technical reports and summaries, contribute written documents for patent applications and manuscripts
  • Maintains broad scientific and technical knowledge within their discipline, and in-depth knowledge relevant to specific drug discovery projects, including state-of-the art principles and theories, new methods and technologies, using the scientific literature to enhance the design and execution of their work
Requirements

  

Education & Experience: 

  • PhD in Immunology, Cell Biology, Biomedical Sciences or related field 
  • 2 years’ productive experience in the biotechnology or pharmaceutical industry in biologics drug discovery; minimum of 
  • 2-4 years’ productive postdoctoral experience in an industry or academic laboratory
  • Demonstrated success in contributing to biologics drug discovery projects, independent and innovative scientific thinking and experimental design/approaches
  • Demonstrated success in designing, analyzing and interpreting results from key experiments, coordinating efforts to achieve project goals
  • Current working knowledge of cellular and molecular immunology, cell biology, or related discipline, with an applied understanding of antibodies and antibody generation, biologics drug discovery research and disease target evaluation
  • Practical state-of-the-art knowledge in the design and implementation of flow cytometry-based multi-color analyses, screening and sorting; practical knowledge of mammalian cell culture, including state-of-the-art cell biology techniques, including cellular signaling and ELISA assays
  • Demonstrated success in project leadership, independent and innovative scientific thinking and experimental design/approaches
  • Strong record of scientific creativity and independence, including a strong scientific publication and external presentation record in accord with years of experience

Competencies: 

  • Effective communication skills, including the ability to independently write study reports and scientific manuscripts for publication, and the ability to make clear oral presentations to project teams and the executive team
  • Ability to multitask, prioritize, and function in a fast-paced entrepreneurial environment
  • Ability to organize work load and activities to achieve corporate and team goals
  • Motivated team player, collaborates with colleagues within and outside of Department, intensely committed to success and getting the job done well in a highly dynamic environment
  • Commitment to high scientific standards and rigorous experimental methods, with strong analytical and problem solving skills
  • Self-motivated and strong work ethic, independent, and results-oriented 
  • Ability to work independently while also willing to take feedback

Physical Demands

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

While performing the duties of this job, the employee is regularly required to sit and talk or hear. The employee frequently is required to use hands to finger, handle, or feel. The employee is occasionally required to stand, walk, and reach with hands and arms. The employee must occasionally lift and/or move up to 10 pounds. Specific vision abilities required by this job include close vision and ability to adjust focus in order to read.

Work Environment

The work environment characteristics are representative of those an employee encounters while performing the essential functions of this job, typically in an open office environment and laboratory. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

The noise level in the work environment is usually moderate.

This position requires working with biological and/or chemical hazards

All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or other legally protected status. 

Salary Description $108k-$139k, 12% bonus, 10% 401k, options & RSU

Company

AnaptysBio is a clinical-stage biotechnology company focused on delivering innovative immunology therapeutics. We are developing immune cell modulators, including two checkpoint agonists in clinical-stage development, for autoimmune and inflammatory disease: rosnilimab, our PD-1 agonist program in a Phase 2 trial for the treatment of moderate-to-severe rheumatoid arthritis; and ANB032, our BTLA agonist program, currently in a Phase 2b trial for the treatment of moderate-to-severe atopic dermatitis. Our preclinical immune cell modulator portfolio includes ANB033, an anti-CD122 antagonist antibody for the treatment of autoimmune and inflammatory diseases. In addition, AnaptysBio has developed two cytokine antagonists available for out-licensing: imsidolimab, an anti-IL-36R antagonist, in Phase 3 for the treatment of generalized pustular psoriasis, or GPP, and etokimab, an anti-IL-33 antagonist for the treatment of respiratory disorders that is Phase 2/3 ready. AnaptysBio has also discovered multiple therapeutic antibodies licensed to GSK in a financial collaboration for immune-oncology, including an anti-PD-1 antagonist antibody (Jemperli (dostarlimab-gxly)), an anti-TIM-3 antagonist antibody (cobolimab, GSK4069889) and an anti-LAG-3 antagonist antibody (GSK4074386).

Our corporate vision is to transform patient health by delivering innovative immunology therapeutics. Find out more about us by following us on Twitter.

 

CONNECT

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Company info
Website
Phone
858-362-6295
Location
10770 Wateridge Circle
Suite 210
San Diego
California
92121
US

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