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Associate Scientist, Translational Sciences

Employer
Neogene Therapeutics
Location
Santa Monica, CA
Start date
Apr 19, 2024

View more

Discipline
Science/R&D, Biotechnology
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Beach, Best Places to Work

Job Details

Pushing the frontier of solid cancer therapy, Neogene Therapeutics is a global, clinical stage biotechnology company built on the premise of innovation and novel paradigm-changing science. Using tumor mutation profiles to engineer fully individualized T cell therapies, Neogene is bringing new hope to address the current limitations of treatments available today.

We offer the opportunity to join a highly dynamic biotech with locations in Amsterdam, Netherlands and in Santa Monica, CA. You can expect a collaborative environment created by a team with deep scientific expertise and an industrial track-record in T cell therapies.

Neogene values pro-active team-players who pursue their goals with dedication, endurance, and a daring mindset. If you share our commitment to make a difference to patients in need, we can provide an exciting opportunity for your career.

Position Summary

Neogene is seeking a highly motivated associate scientist with expertise in NGS, molecular biology, and assay development. The position of Associate Scientist, Translational Sciences is responsible for performing NGS-based assays, sequencing libraries, organizing and analyzing results, and communicating and presenting findings in team meetings. This position is based in Santa Monica, CA and reports to Senior Scientist.

Essential Functions and Responsibilities 

  • Tissue and primary cell preparation into single cell suspension.
  • Performs bulk and single cell NGS workflows such as 10X immunoprofiling.
  • Conducts Illumina library sequencing.
  • Troubleshoots to optimize assay performance and improve robustness.
  • Works independently and as part of a collaborative team to design, plan, and execute assays to support NGS-based projects.
  • Contributes to data tracking and management using ELN.
  • Meets established timeliness, maintains accurate records of work, and clearly communicates results.
  • Presents data within the group and at cross-functional meetings.
  • Assists in other duties as required to meet corporate goals.

Supervisory Responsibilities

  • Not at this time.

Required Skills/Abilities

  • A strong background in genomics and molecular biology.
  • Hand-on expertise in NGS library preparation.
  • Proficiency in single cell NGS platforms.
  • Experience handling Illumina sequencers.
  • Experience with tissue dissociation and primary cell preparation into single cell suspension.
  • Strong organizational and record keeping skills.
  • Team-oriented mindset with ability to work independently and collaboratively.
  • Comfortable in a fast-paced company environment and able to adjust workload based upon changing priorities.
  • Self-motivated and willing to accept temporary responsibilities outside of initial job description.
  • Experience in cell culture aseptic techniques is a plus.
  • Familiarity with bioinformatic pipelines for the analysis of NGS data is a plus.
  • Background in human immunology and cancer immunotherapy is a plus.

Education and Experience

  • BS with a minimum of 7-10 years of lab experience, or MS with and minimum of 5-7 lab experience, or PhD with a minimum of 2 industry experience.

The anticipated salary range for candidates who will work in Santa Monica, CA is $105,000 to $124,000. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job type and length of experience within the industry, education, etc. 

Note: At this time, Neogene is not sponsoring VISAs.

Neogene Therapeutics requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

 

 

DE&I Statement

Headline: We embrace our individual differences.

"Our mission is to build a workforce reflective of our communities to be receptive to patients' broad and unique perspectives, enabling us to empathize with their needs. Together, we strive to uphold a value system that promotes:

  • Opportunities for continuous learning to drive behavioral change and to be respectful of other points of view
  • A collaborative culture that leverages the diverse perspectives of employees and supports courage
  • Zero tolerance for discrimination

We are committed to an emotionally and psychologically safe workplace that trusts employees to boldly explore innovative solutions. We recognize that intentionally embracing diversity at Neogene, empowers us to better relate to patients, and advance our mission to deliver cures where none exist.”

 

Company

Neogene Therapeutics is a global, preclinical stage biotechnology company pioneering the development of next generation, fully individualized engineered T cell therapies for a broad spectrum of cancers.

Our proprietary neoantigen T cell receptor (TCR) discovery and T cell engineering platform identifies TCR genes with specificity for neoantigens – found exclusively on cancer cells as a result of cancer-associated DNA mutations.

Cancer is a genetically individual disease – no two tumors are exactly the same. These variations create neoantigens – unique targets for every tumor. Neogene’s novel approach delivers a tailored T cell therapy containing a unique set of specific TCR genes for each individual patient. Engineered into patient-derived T cells, these TCRs are directed toward neoantigens in tumor cells, with the goal of eliciting strong and durable responses in a variety of solid tumor indications.

We offer the opportunity to join a highly dynamic biotech start-up. You can expect a collaborative environment created by a team with deep scientific expertise and an industrial track-record in T cell therapies. We value pro-active team-players who pursue their goals with dedication, endurance and a daring mindset. If you share our commitment to make a difference to patients in need, we can provide an exciting opportunity for your career.

Company info
Website
Location
2225 Colorado Avenue
Santa Monica
CA
90404
United States

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