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Senior Managing Director

4340 Duncan Ave. Suite 100 St. Louis, MO 63110
Pay is commensurate with experience and is benchmarked against market rates.
Start date
Apr 19, 2024

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Required Education
Position Type
Full time

Job Details

Position Summary: BioGenerator Ventures, the investment and entrepreneur support division of BioSTL, is seeking a Senior Managing Director to play a crucial role in driving the growth and impact of St. Louis' thriving innovation ecosystem. The Senior Managing Director will be responsible for leading BioGenerator Ventures, which includes managing its portfolio of over 70 active companies.

In this pivotal role, the Senior Managing Director will lead BioGenerator Ventures’ ongoing work to create and grow promising new companies in St. Louis —providing investment and comprehensive startup support, including access to the BioGenerator Labs. BioGenerator Ventures' current portfolio is aligned with St. Louis' strengths, including therapeutics, diagnostics, medical devices, agtech, food/nutrition, and healthcare. In 2023, BioGenerator Ventures invested in 23 startup companies, and the portfolio has collectively raised over $2.7B in capital from local, national, and global investors. 

As part of the BioSTL Senior Leadership Team, the Senior Managing Director will help guide the long-term vision and strategic direction of BioSTL, which has been a driving force in developing St. Louis' innovation ecosystem. The position will report to Donn Rubin, BioSTL Founding President and CEO and BioGenerator Ventures’ Chairman. 

Job Responsibilities:

The Senior Managing Director, utilizing scientific, finance, and business experience, will actively participate in the following responsibilities:

• Work with BioSTL Senior Leadership and BioGenerator Managing Directors to manage overall investing and startup support strategy, goals, and portfolio

• Recruit, manage, and mentor the BioGenerator Ventures team 

• Create and build new St. Louis bioscience companies

• Invest in both seed-stage and venture-backed bioscience companies

• Support existing portfolio companies as they advance their products and business models

• Build and support investment syndicates

• Serve on portfolio company boards and help drive portfolio company strategy

• Lead investment due diligence teams

• Improve BioGenerator Ventures’ approaches through new strategies and problem-solving, potentially structuring and raising for-profit investment vehicles

• Work with BioSTL leadership to fulfill the mission of BioSTL in building a world-class innovation economy

• Support all aspects of BioSTL's charitable mission, including education, training, and coaching of talent, and promoting the commercialization of discoveries that improve human health and well-being

• Support philanthropic fundraising for BioSTL to ensure continued resources to achieve its mission

Desired Qualifications/Experience:
• MD or PhD in biosciences or related discipline, or other advanced degree with relevant experience
• 20+ years of professional work experience
• Venture capital investing experience
• Founding and building startup technology companies
• Raising venture capital and private equity, including investment syndicates
• Conducting due diligence on investment and M&A opportunities
• Working in startups and industry
• Managing intellectual property portfolios and negotiating technology licenses
• Creating and launching products and services
• Managing scientific laboratory operations
• Recruiting, training, managing, and developing diverse teams
• Serving on company boards
• Leveraging professional network for diligence and fundraising
• Experience raising, structuring, and managing for-profit funds

• Excellent inquiry, persuasive, collaborative, and communication skills with internal and external audiences
• Ability to excel independently and in a team setting
• Excellent listener
• Ability to see the big picture while focusing on key details
• Excellent judgment and critical thinking
• Prioritization and project planning skills
• Ability to balance risk with opportunity
• Ability to take a non-biased approach to evaluations, focusing on objective information rather than subjective
• Commitment to building an inclusive culture


Pay is commensurate with experience and is benchmarked against market rates. Benefit package for full-time employees includes excellent health coverage, generous retirement savings match, tuition assistance, and other
benefits to support employees personally and professionally.


Please upload a detailed letter of interest and resume on the website under this job posting heading. Confidential inquiries may be submitted to with this job posting title in the subject line.
Please note that this is not a remote position, and successful applicants must reside in the St. Louis region or be willing to immediately relocate to St. Louis.
BioGenerator Ventures and BioSTL are committed to creating a diverse, inclusive, and equitable ecosystem. We are committed to seeking individuals of diverse backgrounds and experiences who will bring a range of perspectives to this work. This is an equal employment opportunity.

About BioSTL:
Since 2001, BioSTL has laid the foundation for St. Louis' innovation economy with a comprehensive set of transformational programs that advance St. Louis’ leadership in solving important world challenges in agriculture, medicine, health care, and other technology areas. BioSTL has introduced nationally acclaimed
initiatives in startup creation and investment (BioGenerator Ventures), strategic business attraction (GlobalSTL), physical environment (including Cortex and BioGenerator Labs), entrepreneur support, seed and venture capital, a diverse and inclusive workforce, and public policy. Find us online at and


Company info
4340 Duncan Ave
Saint Louis

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