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Head of Data Science and Bioinformatics

San Diego, CA
Start date
Apr 12, 2024

Job Details

A career at Resilience is more than just a job – it’s an opportunity to change the future.

Resilience is a technology-focused biomanufacturing company that’s changing the way medicine is made. We’re building a sustainable network of high-tech, end-to-end manufacturing solutions to better withstand disruptive events, serve scientific discovery, and reach those in need.

For more information, please visit

Resilience is seeking an outstanding Head of Data Science and Bioinformatics to lead our personalized medicine platform development in our advanced R&D division. This position will lead a team of bioinformaticians and data scientists developing and leveraging multi-omics assays based on next-generation sequencing (NGS), computer vision, and other advanced analytical approaches. This role requires establishing high-level strategies aligned with the overall vision for the platform establishment and rollout.

Job Responsibilities

  • Lead, develop, and manage a talented bioinformatic and data scientist team.
  • Collaborate with various internal teams, including software, assay development, microfluidics, and systems engineering.
  • Contribute to Resilience’s product vision, roadmap, and portfolio with insights and concepts aligned with the company’s mission of creating excellence in advanced biomanufacturing.
  • Represent the organization in scientific, business, and regulatory meetings and activities. Architect and design bioinformatic workflows with a strong emphasis on scaling and efficiency.
  • Recruit talent (contract and/or full-time) and build high-performance teams, mentors, and coaches’ personnel.
  • Oversee project execution (resourcing, planning, and delivery) and guide the organization through changing market /product needs and requirements
  • Collaborates with the research scientists and engineering teams towards optimizing our workflows, assays, and instruments.
  • Provides bioinformatics and data science subject matter expertise in the planning and execution of cell and gene therapy projects that require advanced analytics methods, ensuring the maximum value is realized for data generated.
  • Provide in-depth statistical and data analytical expertise across the organization by collaborating with Research, Development, Quality, Manufacturing, and Sciences Teams.
  • Work with the Quality Engineering group to ensure that the team follows appropriate GMP, design history file (DHF), and device history record (DHR) guidelines per FDA requirements and support design reviews according to product development procedures.

Minimum Qualifications

  • Hands-on experience in building and managing teams that provide bioinformatics and data science solutions.
  • Demonstrated ability to set goals, perform long-term project planning, team building, budgeting, and operational excellence
  • Demonstrated ability to execute responsibilities in a fast-paced environment, collaborating across multiple sites and stakeholders.
  • Ability to communicate effectively and professionally across various technical disciplines with multiple stakeholders, including management, peers, customers, and suppliers.
  • Extensive experience in developing NGS Bioinformatics applications with demonstrated lead developer skills in programming languages such as Python, R, Go, and Nextflow.
  • Experience in verification, validation, and deployment into a regulated environment (CLIA/CAP, GxP, medical devices, etc.).
  • Demonstrated ability to perform long-term project planning, including designing bioinformatics and data science-centric architecture.
  • Ability to communicate effectively and professionally across various technical disciplines with multiple stakeholders, including management, peers, customers, and suppliers.
  • Good organizational skills, with the ability to simultaneously contribute to multiple fast-paced projects.
  • Deep understanding of NGS-based assay development processes, algorithms, and workflows, including those related to microbial, RNASeq, and single-cell multi-omics applications.
  • Experience in immunology and/or cancer research applications is a plus.

Preferred Experience

  • MSc. or PhD in Bioinformatics, Computational Biology, Computer Science, Software Engineering, or related field. Typically, a Director will have at least ten years or more of relevant industry experience.
  • Experience in metagenomics bioinformatics and assays in clinical settings.
  • Experience with various single-cell data types, including transcriptomics, proteomics, and epigenomics data.
  • Experience applying machine learning techniques to single-cell data, including the ability to select appropriate algorithms and evaluate their performance.
  • Experience in Agile and/or Product Development Process (PDP).

Resilience is an Equal Employment Opportunity Employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender perception or identity, national origin, age, marital status, protected veteran status, disability status, physical or mental disability, genetic information, or characteristic, or other non-job-related characteristics or other prohibited grounds specified in applicable federal, state, and local laws. Requests for reasonable accommodation can be made at any stage of the recruitment process.

Resilience offers employees a robust total rewards program including equity, an annual cash bonus program, a 401(k) plan with a generous company match and our benefits package which is thoughtfully designed to support our employees with great healthcare (including medical, dental and vision), family building benefits, life and disability insurance, flexible time off, paid holidays, other paid leaves of absence, tuition reimbursement and support for caregiving needs. Our target base pay hiring range for this position is $190,000.00 - $257,500.00 per year. Actual base pay is dependent upon a number of factors, including but not limited to, the candidate’s geographical location, relevant experience, qualifications, skills and knowledge. Excited about Resilience and the biomanufacturing revolution? We encourage you to apply and start a conversation with one of our recruiters.


Resilience is a technology-focused biomanufacturing company dedicated to broadening access to complex medicines. Founded in 2020, the company is building a sustainable network of high-tech, end-to-end manufacturing solutions to ensure the treatments of today and tomorrow can be made quickly, safely, and at scale. Resilience seeks to free its partners to focus on the discoveries that improve patients’ lives by continuously advancing the science of biopharmaceutical manufacturing and development. For more information, visit and follow us on Twitter @IncResilience 

Company info
9310 Athena Circles
La Jolla

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