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Process Development Senior Scientist

Thousand Oaks, California
Start date
Apr 6, 2024

Job Details


Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Process Development Senior Scientist


What you will do

Lets do this! Lets change the world!

The Structure Elucidation team within Attribute Sciences, provides NMR expertise for Amgens clinical and commercial portfolio. Amgen is currently seeking a Senior Scientist in our Thousand Oaks facility. The successful candidate will be primarily responsible for (1) providing NMR expertise in the analysis of synthetic molecules, which may involve starting materials, intermediates, impurities, degradation products, and active pharmaceutical ingredients, (2) supporting the NMR reaction monitoring for chemical process understanding, 3D structural analysis, and quantitative NMR, and (3) further developing applications for benchtop NMR systems. The team provides support for hybrid and biologic modalities and is also accountable for supporting the structural elucidation component for regulatory filings.

By applying and developing NMR methodologies, the Scientist will work closely with analytical and organic chemists supporting chemical and biological processes to understand key aspects of synthetic products, manufacturing, and biologics. The Scientist will work in collaboration with NMR structural elucidation scientists across the Amgen network. Our laboratories are equipped with state-of-the art NMR instrumentation.

Key Responsibilities
  • Structural elucidation of small molecules (organics) using state-of-the-art NMR methodologies

  • Structure characterization of APIs, reference standards, synthetic impurities, and degradation products in GLP and GMP environments

  • Development of applications for benchtop NMR systems.

  • Collaboration with project teams in Process Development

  • NMR analysis of hybrid and biological modalities

  • qNMR support and training for purity assay

  • Forensic investigations using NMR

  • Authoring for the elucidation of structure section of CMC regulatory filing for small molecule programs


What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is an individual with these qualifications.

Basic Qualifications
  • Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] OR

  • Masters degree and 3 years of NMR experience OR

  • Bachelors degree and 5 years of NMR experience

Preferred Qualifications
  • Ph.D. in chemistry or equivalent with at least 2 years of relevant experience in NMR spectroscopy preferable in the pharmaceutical industry

  • Proven hands-on experience in small-molecule NMR spectroscopy

  • Strong background in organic chemistry and structure elucidation

  • Expertise on NMR methods with proficiency on NMR data systems and pulse sequence language

  • Basic understanding of GLP and GMP requirements

  • Strong written and communication abilities

  • Ability to collaborate with project teams in fast-paced team environments

  • Work well with cross-functional teams, across various geographic locations, in different time zones


What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates professional and personal growth and well-being.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

  • Stock-based long-term incentives

  • Award-winning time-off plans and bi-annual company-wide shutdowns

  • Flexible work models, including remote work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.


We are all different, yet we have this in common: our mission to serve patients. This sense of shared purpose is key to our becoming one of the world’s leading biotechnology companies. It guides us as we continue to launch new medicines and reach millions of patients worldwide.

We live the mission.

We win together.

We thrive on continual challenge.

Our team of 22,000+ scientists and professionals worldwide bring distinct perspectives and experiences to all we do. We leverage our global talent to achieve together—to research, manufacture and deliver ever-better products and greater depth to our mission.

At Amgen, there is a strong correlation between our high level of diversity and performance. Because addressing issues with a wider range of perspectives and approaches leads to more creative problem-solving. Together, we’re transforming the promise of science and biotechnology into therapies that have the power to restore health.

Connect with us to explore how you can Win, Live, and Thrive at Amgen.

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Company info
Corporate Headquarters
One Amgen Center Drive
Thousand Oaks

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