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Sr. Research Scientist II, Protein Therapeutics

Gilead Sciences, Inc.
Foster City, CA
Start date
Apr 3, 2024

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Job Details

Sr. Research Scientist II, Protein Therapeutics
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead’s therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company’s five core values. That’s because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible

For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.

We empower our leaders to step up, share ideas, listen, learn, and lead. We're welcoming bright, diverse, and imaginative minds; we're nurturing them to foster an environment of inclusion and growth where innovation is encouraged. We expect our people leaders to model that environment, and to focus on creating inclusion, developing talent, and enabling teams.

Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact. Join Gilead and help create possible, together.
Job Description

Protein Therapeutics, the biologics discovery function within Gilead Research, is seeking an experienced and laboratory-facing senior research scientist to join the Protein Science team to expand our research cell line engineering function. The successful candidate will apply state-of-the-art synthetic biology and cell engineering techniques to create research cell lines for recombinant protein production to support drug candidate screening in vitro and in vivo across Gilead's therapeutic areas including Virology, Oncology, and Inflammation. He/she will also be accountable for developing membrane protein target-expressing cell lines to support Protein Therapeutics' internal antibody discovery and screening activities. Importantly, this strategic position will represent Protein Therapeutics to partner with Gilead Pharmaceutical Development and Manufacturing organization to refine and streamline the next-generation CHO cell line development process to expeditiously advance biologics programs from Research to Development.


  • Expand research cell line generation function to support antibody discovery activities from target expression, candidate production, and screening cell line engineering
  • Serve as subject matter expert in cell line engineering technologies. Propose, evaluate, and implement new technologies to expedite the timeline from sequence to protein expression
  • Employ functional genomics approach to enhance cellular processes in platform cell line to improve expression of target molecules
  • Support Protein Therapeutic to advance the biologics discovery campaigns from target ideation to preclinical development
  • Partner with Gilead Pharmaceutical Development and Manufacturing organization to build the next-generation CHO cell line platform
  • Provide scientific data to support publications and patent filings, present in internal and external team meetings
  • Present findings to project teams and senior management regularly
  • Mentor and develop team members


  • Highly motivated individual with Ph.D. in Biochemical Engineering, Synthetic Biology, or related disciplines with 5 or substantially more years of biopharmaceutical experience
  • Proven track record and extensive hands-on experience in cell line (including CHO) and process developments for research purposes from sequence to production
  • Experience with genetic engineering, CRISPR/Cas editing in mammalian cell line generation
  • Expertise in multispanning membrane protein expression by recombinant cells is desirable. Skills in membrane protein preparation will be highly valued
  • Independent scientific thinking and data management skills
  • Excellent verbal and written communication skills.
  • Demonstrated ability to work independently and effectively on multiple programs in a fast-paced and matrixed organization
  • Supervisory experience managing scientists and workflows is expected

The salary range for this position is: $191,335.00 - $247,610.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

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As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact for assistance.

For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.



Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.



Gilead Sciences is a biopharmaceutical company that discovers, develops, and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide. Headquartered in Foster City, California, Gilead has operations in North America, Europe and Australia.

Company info
333 Lakeside Drive
Foster City

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