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Research Scientist II, Inflammation Discovery Research

San Diego, CA
Start date
Mar 30, 2024

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Regulatory, Science/R&D, Biotechnology, Research
Required Education
Bachelors Degree
Position Type
Full time
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Job Details

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

About the role:

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.

Join Takeda as a Research Scientist II, Inflammation Discovery Research where you will be empowered to design, execute and analyze discovery immunology and in vitro preclinical pharmacology studies of inflammation and autoimmunity with a focus on TYK2 inhibition for multiple disease indications. You will also identify and implement new assay technologies that have an impact on project advancement, assay throughput and/or assay performance. As part of the GI and Inflammation Drug Discovery Unit (GI² DDU), you will report to the Associate Director and work with the organization.

How you will contribute:
  • Initiate investigation of new experimental approaches to a wide range of problems using scientific theory and technical literature with a focus on TYK2 pathway.
  • Utilize a battery of in vitro assay technologies in primary cell types and cell lines to execute on programs including (but not limited to): ELISA, qPCR, flow cytometry, immunofluorescence microscopy.
  • Design and execute complex cell-based assays including co-cultures, 3D microtissues / organoids.
  • Independently plan and execute experiments for a research work group or project, troubleshoots complex problems and/or specialized procedures, and changes experimental design if necessary.
  • Interpret and analyze data, to incorporate results into overall scientific projects; Independently generate novel hypothesis and integrates data produced by other disciplines.
  • Develop and validate new technical and analytical methods using literature.
  • Exercise independent judgement (selecting most appropriate methods, coordinating efforts, evaluating criteria for obtaining results).
  • Prepare detailed protocols / SOPs that enable transfer of validated assays to project team members and collaborators.
  • Work with flow cytometry, in vivo pharmacology, histopathology, and bioinformatics team to evaluate cell and molecular action of TYK2 inhibition.
  • Contribute to functional scientific discussion.
  • Maintain detailed laboratory records and contribute to drafting of study reports.
  • 80% lab based at the San Diego facility.

Minimum Requirements/Qualifications:
  • PhD degree in a scientific discipline with 2+years relevant experience; post doc and industry experience preferred, or MS with 8+ years experience, or BS with 10+ years experience.
  • Demonstrate significant knowledge of basic Immunology and in vivo pharmacology.
  • Communicate and collaborate with colleagues effectively.
  • Knowledge in the use of common analytic softwares including Microsoft Office programs, Graphpad Prizm etc.
  • With latitude in specific areas, plans and executes experiments with appropriate controls; decisions have moderate to advanced scope and impact technical operations or project deadlines.

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.



Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

San Diego, CA

U.S. Base Salary Range:

$133,000.00 - $209,000.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.


San Diego, CA

Worker Type


Worker Sub-Type


Time Type

Full time


Takeda is a global, values-based, R&D-driven biopharmaceutical leader headquartered in Japan, committed to discover and deliver life-transforming treatments, guided by our commitment to patients, our people and the planet. Takeda focuses its R&D efforts on four therapeutic areas: Oncology, Rare Genetics and Hematology, Neuroscience, and Gastroenterology (GI). We also make targeted R&D investments in Plasma-Derived Therapies and Vaccines. We are focusing on developing highly innovative medicines that contribute to making a difference in people’s lives by advancing the frontier of new treatment options and leveraging our enhanced collaborative R&D engine and capabilities to create a robust, modality-diverse pipeline. Our employees are committed to improving quality of life for patients and to working with our partners in health care in approximately 80 countries and regions.

For more information, visit

Stock Symbol: TAK

Company info
650 East Kendall Street

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