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Research and Early Development Postdoctoral Fellowship

Employer
BioMarin Pharmaceutical Inc.
Location
San Rafael, California
Start date
Mar 25, 2024

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Job Details

Job Description: RED Postdoctoral Fellow    BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious or life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.

    The Research and Early Development (RED) organization at BioMarin conducts trail-blazing research to enable preclinical drug development for patients with genetic diseases in the cardiovascular, hematology, musculoskeletal and central nervous system therapeutic areas. We leverage multiple modalities, including biologics, small molecules, oligonucleotides and gene therapy. We work with world-class academic investigators and centers and a diverse array of internal research and development partners in genomics, gene editing and translational sciences. ​

    We are currently seeking qualified and motivated individuals to join BioMarin as  Postdoctoral Fellows in one of the following departments within RED:     Research: Musculoskeletal, Hematology, Cardiovascular, Neuroscience, Genomics, Delivery, or Gene Therapy    Translational Sciences: Clinical Pharmacology, Clinical Immunology, Pharmacological Sciences, or Bioanalytical Sciences    Fellows will be matched to one department within RED for a two-year term.  While gaining technical experience, fellows will also be introduced to other biotech business units including Regulatory, Product Portfolio Development, Clinical Sciences, and Medical Affairs.        To Apply    
  • Along with your CV/resume, please submit a Letter of Intent. Your Letter of Intent should include which Research or Translational Science department (noted above) you’d like to join and a description of the areas of research or drug development you’d like to pursue during the fellowship. 
    Responsibilities    
  • Design and conduct experiments or studies in collaboration with the Fellowship advisor and/or RED or Clinical colleagues to advance a pipeline program or platform, or to identify and explore new indications, modalities, or technologies.
  • Provide scientific and intellectual input to guide project-related proof-of-concept and investigative efforts within the context of interdisciplinary project teams.
  • Where appropriate, initiate, direct and execute the development, optimization, and qualification of robust assays.
  • Analyze data with applicable bioinformatics tools/scientifically sound interpretation and present data at group/departmental meetings.
  • Troubleshoot experiments based on a thorough understanding of assay principles.
  • Author technical reports and SOPs associated with the assays developed and qualified.
  • Contribute to study reports and manuscripts.
  • Provide scientific support to collaborating functional groups, as needed.
  • Work with junior research associates and scientists on experimental design, troubleshooting, assay optimization and data interpretation, where applicable.
  • Maintains broad knowledge of relevant state-of-the-art principles and theories.
  • Participate in exploratory studies driving the evaluation of state-of-the-art technology platforms, and innovative upgrades for existing assay platforms.
  • Identify, develop and maintain relationships with contract research organizations to maximize project productivity and assure inclusion of latest scientific thinking and guidelines in the research plan.
    
  • Contribute to the peer review process, both internally and externally, to help assure BioMarin research is conducted at the highest level of quality, integrating business and development objectives.
  • Makes major contributions to scientific literature and conferences.
  • Participate in at least one governance meeting and/or regulatory engagement on a pipeline program​.
  • Present at/participate in program/platform strategy meetings​.
  • Opportunities for project-based rotations, as appropriate (within or outside of the department) based on the Fellow’s interests and corresponding business needs.
        Education Requirements    Completion of a doctoral degree in a relevant scientific discipline within three years of the program start date (June 2024);​ no industry experience required.​         General Requirements        
  • Track record of success demonstrated by a strong publication record.
  • Demonstrates professional maturity, treats others equitably and fairly, and is willing to adhere to BioMarin Code of Conduct.
  • Robust track record of demonstrating self-initiative/motivation.
  • Highly self-motivated, detail-oriented, and possess excellent written and oral communication skills.
  • Well-organized with the ability to be flexible and work in a fast-paced environment with competing priorities.
  • Ability to think strategically.
  • Strong interpersonal skills and the ability to work in a team-oriented environment.
  • Be able to navigate a new working environment in parallel with personal development.
  • Demonstrates the skill to analyze and synthesize data with efficiency and effectiveness.
  • Effectively deals with ambiguity and adapts quickly to change.
  • Excellent collaboration and interpersonal skills.
  • Works independently on complex projects.
     Benefits of a Postdoctoral Scientist     Provides individuals interested in research careers in industry further training so they have the opportunity to hone technical skills, focus research interests and develop independence.         We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.        

Company

BioMarin is a global biotechnology company dedicated to transforming lives through genetic discovery. In 1997, the company was founded to make a big difference in small patient populations, focusing on giving much-needed attention to the underserved communities of those with rare diseases. BioMarin sought to help patients whose voices could not always be heard and treat conditions that were not always in mainstream medical conversations. Throughout its history, BioMarin has worked tirelessly to make a difference by pursuing bold science. The company’s first approved therapy was inspired by a father who refused to accept there was no therapy for his son’s rare diagnosis. That relentless pursuit to change the course of his son’s future through the power of science is at the core of who BioMarin is today.

Through the company’s expertise in genetics and molecular biology, BioMarin has developed eight first or best-in-class targeted therapies that address the root cause of the conditions it seeks to treat, helping to better the lives of those struggling with rare genetic disease. The company’s purposeful and scientifically precise team of physicians and scientists has honed each treatment modality to seek transformative therapies.

Now, BioMarin seeks to make an even greater impact by applying the same science-driven, patient-forward approach that propelled the last 25 plus years of drug development to larger genetic disorders, as well as genetic subsets of more common conditions. Each drug candidate pursued is guided by a fundamental understanding of the genetics and underlying biology of the condition it will address. The company believes that applying its knowledge to make a transformative impact is not just a calling, but an obligation to those who will benefit most. The more innovative solutions developed, the more lives BioMarin can impact.

Company info
Website
Location
California
United States

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