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Executive Director, Program Leader, Rare Disease

Moderna, Inc.
Cambridge, MA
Start date
Mar 21, 2024

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Science/R&D, Pathology
Required Education
Bachelors Degree
Position Type
Full time
Genetown, Best Places to Work

Job Details

The Role:

mRNA has promise in several areas of Internal Medicine, including Cardiovascular, Pulmonary, Hematology and invasive indications. We seek an agile clinical developer to lead as we interrogate and prosecute those diseases where mRNA has transformative potential.

Moderna is seeking a motivated and energetic Program Leader for our Rare Disease programs to drive the program strategy and maintain accountability of program execution. The successful candidate will work in close coordination with the program manager to drive the strategy of the program and enable the execution of the set timelines. The Program Leader will lead a cross-functional team across clinical operations, regulatory affairs, clinical pharmacology, biomarkers, CMC, non-clinical, and medical to deliver against the program strategy. The successful candidate will have experience in late-stage readiness and development of Rare Disease programs.

The successful candidate is able to work independently and thrive in a proactive can-do culture and team milieu to lead the clinical development activities for mRNA-based therapies for our current Rare Disease programs while leveraging success in those to catalyze development across the most promising Rare Disease for mRNA therapy with unmet medical need. You will work closely with colleagues across Development including autoimmune disease, Rare Disease and immuno-oncology, while also having a change to interact with colleagues in infectious disease. The candidates will be a highly effective internal and external team player and terrific communicator and collaborator.

Heres What Youll Do:

The Program Leader will be involved in high-level leadership of the assigned program(s):

  • Lead the cross-functional teams for a Rare Disease program(s)

  • Represent the program status, scenarios, and trade-offs with senior leadership, internal stakeholders, and external stakeholders

  • Align on a program direction in coordination with senior functional leaders and program representatives

  • Support development of regulatory documents and HA interactions

  • Engage external stakeholders including KOLs and key PIs; engage advisory boards in order to develop an effective program strategy

  • Accountable for the integrated development plan for the Rare Disease program(s)

  • Develop a program budget in coordination with the program manager, finance and functional representatives; identify trade-offs

  • Work with senior leadership to support late-stage development activities including endpoints for registration, patient reported outcomes, and health-economics

  • Work with corporate affairs to continue patient advocacy efforts for both Inborn Errors of Metabolism

Heres What Youll Bring to the Table:

  • BS/MS degree in a scientific field with 10+ years of experience or Ph.D or MD with 5-8 years of experience in a biotechnology or pharmaceutical setting

  • Experience in Rare Disease drug development including the transition of novel candidates from discovery through licensure

  • Proven track record of successful cross functional program leadership or management supporting early- and late-stage programs

  • Strong ability to lead cross-functional teams; engage senior leadership, health authorities, and KOLs

  • Prior experience managing or working within cross-functional project teams with timeline management and budgetary responsibility

  • Must be adept at working in a fluid environment and foster a strong collaborative spirit internally and externally.

  • Strong written and oral communication skills as well as demonstrated organizationalaptitude

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

  • Highly competitive and inclusive medical, dental and vision coverage options
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
  • Family care benefits, including subsidized back-up care options and on-demand tutoring
  • Free premium access to fitness, nutrition, and mindfulness classes
  • Exclusive preferred pricing on Peloton fitness equipment
  • Adoption and family-planning benefits
  • Dedicated care coordination support for our LGBTQ+ community
  • Generous paid time off, including:
    Vacation, sick time and holidays
    Volunteer time to participate within your community
    Discretionary year-end shutdown
    Paid sabbatical after 5 years; every 3 years thereafter
  • Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
  • 401k match and Financial Planning tools
  • Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
  • Complimentary concierge service including home services research, travel booking, and entertainment requests
  • Free parking or subsidized commuter passes
  • Location-specific perks and extras!

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, theinfrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our peopleare the driving force behind our scientific progress and our culture.Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute and make a meaningful impact.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit to learn more about our current opportunities.

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. Were focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at (EEO/AAP Employer)




Moderna is advancing messenger RNA (mRNA) science to create a new class of transformative medicines for patients. Moderna’s platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, providing the Company the capability to pursue in parallel a robust pipeline of new development candidates. Moderna is developing therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases and cardiovascular diseases, independently and with strategic collaborators.

mRNA is now a turning point in the history of science, medicine, technology, even humankind itself. With this breakthrough discovery, many of the world’s biggest and most challenging medical problems are no longer a question of “how?” but merely a question of “when?”

Come with us as we pursue the uncharted reaches of possibility and make your mark on the future of medicine.


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Company info
200 Technology Square
Cambridge, MA

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