Skip to main content

This job has expired

You will need to login before you can apply for a job.

Sr. Lab Manager

Vaxcyte, Inc.
San Carlos, California
Start date
Mar 16, 2024

View more

Science/R&D, Research, Laboratory
Required Education
Bachelors Degree
Position Type
Full time
Biotech Bay

Job Details

Join our Mission to Protect Humankind!

Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, periodontitis and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance. 

WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values:

*AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.

*LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.

*RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.

*MODEL EXCELLENCE:  The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.
Vaxcyte is seeking a highly energetic, talented, pro-active, and self-motivated individual to join our growing Facilities and Lab Operations Team. The Senior Lab Manager is a very hands-on role and is responsible for the overall daily operations in Vaxcyte laboratories including vendor management, lab supply inventory, equipment maintenance requirements, and new equipment orders. The Lab Manager is a critical point of contact for lab personnel, fielding service requests, triaging and assigning tasks, providing training, and helping to maintain a culture of safety and compliance. They will support general lab space equipment layouts. They will work with appropriate departments on the development of necessary SOPs for training, equipment maintenance, calibration, and repair. They will work closely with procurement and the lab teams on CAPEX / OPEX budgeting and ordering of lab assets and service contracts. They will support installations in lab spaces, and oversight of any qualification / validation verification activities. They will provide feedback on lab efficiency, operations, and policies as well as recommendations on any necessary changes or improvement.
This role will be instrumental in ensuring our facilities and lab operations department and laboratories are ready for growth with Vaxcyte’s current and projected product pipelines. This department enables the labs to run efficiently and the scientists to focus on delivering their respective pipelines. This role will own this department’s transformational journey including centralizing lab operations, standardizing common services, consolidating supplies, implementation of GMP and contracts and application of lean lab techniques (e.g., 5S, Kanban, visual management).  A successful candidate is well organized, flexible, creative and enjoys the challenges of managing a diverse and energetic office space. This is a full-time, on-site role that reports to the Director of Lab Operations
Note: rotational, shared 24x7 support is required of this role.
Essential Functions:
    • Establish and maintain an infrastructure to enable a structured laboratory operation. framework across Vaxcyte’s labs including capital plan/expenditures (from forecast to installation), lab equipment and instrumentation (i.e., contracts, maintenance, repair, calibration, upgrade and retiring), and lab consumables (i.e., contracts, procurement, order management, inventory management).
    • Provide strategic direction, technical supervision, and support to the lab operations team who supports day-to-day operations. Lead operational performance reviews and establish business / individual objectives.
    • Drive improvements in service level, efficiency and cost reduction through standardization of common practices, implementation lean lab techniques and utilization of metrics. Create a platform to share ideas within the lab operations team and with clients including the application of best practices. Establish relationships and service standards and coverage to meet lab-based personnel’s needs.
    • Establish and own a laboratory business continuity plan as well as extended-hours coverage and response plan.
    • Build and improve relationships with partners (i.e., Research Associates, Scientists) and key functions within Vaxcyte (i.e., Project Management, Procurement, Legal, Accounts Payable) through proactive engagement and communication.
    • Develop and realize a service model with clear roles and responsibilities and decision making.
    • Accountable for overall delivery and performance across lab operations.
    • In Collaboration with lab leadership, proactively identify and resolve risks/issues.
    • Responsible for developing and executing a strategy for servicing laboratories, including equipment and instrumentation, scheduling, and lab capacity utilization.
    • Establish relationships and service standards and coverage to meet lab-based personnel’s needs.
    • Support the development, budgeting, and execution of a three (3) year capital project plan.
    • Establish common practices to obtain quotes, submit contract for legal review, place orders, prepare for location set-up (Preparation of bench space, request IT support on computer and network, request Facilities support on utilities), manage equipment delivery, installation, and set-up for use.
    • Establish and manage a common model and contracting strategy across lab operations for equipment preventative maintenance/calibrations/repair, asset utilization, asset surplus redeployment, system upgrade, and retiring with customers, Lab Operations staff, and third-party vendors, to create and manage a list of equipment that is in use and also that scientists can have ready access to Lab Consumables & Critical Supplies.
    • Work with laboratory staff and third-party vendors, to create and manage a master list of managed items onsite (by vendors and internally), stock locations, and stock levels to ensure that scientists have ready access to all basic consumables, critical materials.
    • Partner with key stakeholders to develop and continuously strive for a proactive, high bar safety culture.
    • Work with EH&S Manager to manage EH&S programs at the site to include, but not limited to, Incident Management, Ergonomics, Exposure Risk Assessments, Chemical Hygiene, Hazard Communication, Biosafety Management, Respiratory Protection, Hearing Conservation and Personal Protective Equipment (PPE), etc.
    • Work with EH&S Manager to ensure the site is compliant with all environmental and safety regulations, including Federal, State and/or City regulations.

    • Bachelor’s degree in Science or Engineering related discipline.
    • 7 years of progressive experience in operational leadership in R&D and GMP/GLP laboratory, biotechnology or pharmaceutical environment.
    • 3+ years of proven success leading teams of lab operations staff or vendors.
    • Proven track record in managing and scaling lab operations.
    • Understand laboratory supply streams, waste streams, and have experience working in an R&D and GMP and GLP laboratory environment.
    • Is known for being highly customer service oriented and has a track record of anticipating the needs of all customers, including bench scientists.
    • Demonstrated drive, curiosity, scientific rigor, and excellent problem-solving skills across a fast-paced performance driven environment.
    • Ability to operate effectively at both an operational and strategic level.
    • Ability to constructively challenge, improve and develop lab operations practices and processes.
    • Self-motivated with the proven ability to take ownership and deliver results in an environment with ambiguity and change.
    • Ability to collaborate cross functionally and align stakeholders to a common problem or solution.
    • Superior communication and interpersonal skills – Oral, written and formal presentation skills.
    • Demonstrated ability to develop new lab operations practices (from a blank sheet of paper) and standard operating procedures.
    • Highly effective communication and organization skills.
    • Proven collaboration and teamwork skills and experience in a fast-paced environment.
    • Creative and proactive problem solver; keen ability to anticipate needs in a lab environment, solving problems with sound judgment.
    • Experience managing and prioritizing inputs from diverse stakeholders to deploy a plan that meets the needs of the business.
    • Proficiency planning and managing small projects.
    • Proficient in GMP, GLP, and GDP.
    • All Vaxcyte employees require vaccination against COVID-19.

Reports to: Director, Lab Operations
Location: San Carlos, CA
The compensation package will be competitive and includes comprehensive benefits and an equity component.
Salary Range: $146,000 – $156,000


Vaxcyte, Inc. (Nasdaq: PCVX) is a next-generation vaccine company seeking to improve global health by developing superior and novel vaccines designed to prevent some of the most common and deadly infectious diseases worldwide. Our exclusively licensed cell-free protein synthesis platform and our proprietary know how enable us to design and produce optimized protein carriers and antigens, the critical building blocks of vaccines, in ways that we believe conventional vaccine technologies cannot. Our lead vaccine candidate, VAX-24, is a preclinical, 24-valent broad-spectrum pneumococcal conjugate vaccine (PCV) being developed for the prevention of invasive pneumococcal disease. Our pipeline also includes VAX-XP, a PCV with an expanded breadth of coverage of at least 30 strains; VAX-A1, a prophylactic vaccine candidate designed to prevent Group A Strep infections; and VAX-PG, a therapeutic vaccine candidate designed to slow or stop the progression of periodontal disease by targeting the keystone pathogen responsible for this chronic, oral inflammatory disease.

Company info
(650) 837-0111
825 Industrial Road, Suite 300
San Carlos

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert