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Biologist - Protein Engineering

Eli Lilly and Company
San Diego, California
Start date
Mar 1, 2024

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Science/R&D, Biology
Required Education
Bachelors Degree
Position Type
Full time
Biotech Beach, Best Places to Work

Job Details

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

The Biotechnology Discovery Research Division in San Diego is responsible for generating, characterizing, and optimizing biotherapeutics from lead generation through lead optimization and preclinical development. We support cross-disciplinary efforts to engineer innovative biotherapeutics that treat metabolic, autoimmune, oncologic, and neurologic diseases. Join our team of scientists working to improve the lives of patients around the world.

This is an opportunity for a self-motivated researcher to join the Protein Engineering and Computational Sciences Group at the Lilly Biotechnology Center in San Diego. We are seeking an associate level scientist with experience in Molecular Biology, Biochemistry and Protein Engineering. The ideal candidate is a highly dedicated teammate with outstanding technical skills who can work collaboratively with the antibody discovery, protein engineering, protein production, protein characterization, and automation groups in San Diego and Indianapolis.


  • Think creatively and assist in designing and performing experiments to identify and validate the next generation of large molecule therapeutics

  • Conceive, contribute, and execute in creating and improving next-generation technology platforms to deliver tomorrow’s therapeutics

  • Engineer, characterize, and optimize antibodies, bispecifics, therapeutic proteins, and conjugates

  • Work collaboratively and communicate with project teams to achieve critical research objectives and timelines

  • Maintain diligent, detailed, and well-organized records including electronic notebooks, laboratory information management systems, presentations, and reports

Basic Requirements:

  • Bachelor’s degree in Biological Sciences or related field (Biochemistry, Structural Biology, Biotechnology, Cell Biology) with relevant laboratory experience or training

Additional Skills/Preferences:

  • Experience with molecular biology, cloning, PCR, restriction enzyme/ligase and recombination-based cloning, small-scale plasmid DNA extractions and protein production/analysis highly desired

  • Knowledge/experience in ELISAs, cell culture, and cell-based binding assays

  • Knowledge of antibody discovery and engineering, protein structure, and biochemistry

  • Experience working with automation and documenting/analyzing large data sets

  • Effective interpersonal skills, including written and oral communication skills

  • Self-motivated, strong work ethic, independent, and results-oriented

  • Excellent analytical and organizational skills and high attention to detail

  • Ability to work independently as well as in cross-functional team settings is essential

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.



Science has been our calling from the beginning. Colonel Eli Lilly founded the company in 1876 and charged employees to “take what you find here and make it better and better.” More than 147 years later, we remain committed to his vision through every aspect of our business and the people we serve, starting with discovering the best treatments for those who take our medicines and extending to health care professionals, employees and the communities in which we live. Moreover, you can also count on the team at Lilly to be incredibly civic-minded, supporting our communities through philanthropy, volunteerism, and a creative and innovative can-do spirit. 

Company info
893 S Delaware St
United States

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