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Research Associate II, In Vitro Pharmacology (Contract)

Employer
ReCode Therapeutics
Location
Menlo Park, California
Start date
Mar 1, 2024

View more

Discipline
Regulatory, Science/R&D, Research, Pharmacology
Required Education
Bachelors Degree
Position Type
Contract
Hotbed
Biotech Bay

Job Details

Who We Are:

ReCode Therapeutics is a clinical-stage genetic medicines company using precision delivery to power the next wave of mRNA and gene correction therapeutics. ReCode’s proprietary Selective Organ Targeting (SORT) lipid nanoparticle (LNP) platform enables highly precise and targeted delivery of genetic medicines directly to the organs, tissues and cells implicated in disease, enabling improved efficacy and potency. ReCode’s lead programs include RCT1100 for the treatment of primary ciliary dyskinesia caused by pathogenic mutations in the DNAI1 gene, and RCT2100 for the treatment of the 10-13% of cystic fibrosis patients who have Class I mutations in the CFTR gene and do not respond to currently approved CFTR modulators. RCT1100 and RCT2100 are inhaled disease-modifying mRNA-based therapies formulated using the SORT LNP delivery platform. ReCode is expanding its pipeline to develop potential therapies for other rare and common genetic diseases, including musculoskeletal, central nervous system, liver and infectious disease indications.

Summary of Position:

We are seeking a highly motivated individual to join the In Vitro Pharmacology team. The primary responsibilities of this role will be to plan, perform and analyze experiments to support the discovery and development of new therapeutics. The successful candidate will collaborate with an inter-disciplinary team of ReCode scientists and will have access to excellent experimental and analytical facilities. This is a contract position based in Menlo Park.

Responsibilities:

  • Perform cell culture work, including thawing, maintaining, expanding, cryopreserving immortalized cell lines.
  • Plan and execute cell-based assays (transfection, cell viability, flow cytometry, and immunofluorescence).
  • Perform protein isolation from mammalian cells.
  • Analyze protein expression through techniques like western blot, JESS and ELISA.
  • Prepare aliquots of media, PBS, antibodies, supplements, and inventory management.
  • Follow standard operating procedures, maintain accurate records, and adhere to safety protocols.
  • Coordinate with fellow researchers within the team to plan for cell culture requirements.
  • Plan and perform experiments and analyze data with supervision.
  • Present data at group meetings.
  • Contribute to lab management activities.

Qualifications:

  • Bachelor’s/Master's degree in biology or related field with 2+ years of lab experience in the biopharma industry.
  • Proven hands-on experience with sterile technique for handling and growing mammalian cell lines.
  • Demonstrated experience with techniques: Protein isolation, western blot/JESS, immunofluorescence, and cell-based assays.
  • Ability to work independently and in a team-oriented environment to meet project goals and timelines.
  • Strong verbal and written communication skills.
  • Strong troubleshooting, and problem-solving skills
  • Desire to work in a fast-paced environment.

Salary Range: $45-$50/hr

Benefits Offered for Full-Time Employees: 

  • No premium cost for employees - 100% subsidized by ReCode for full-time employees
  • Company 401k contribution
  • 15 days of company paid holidays, including a holiday shutdown (usually the last week of the year)
  • Mental health support for employees & their families
  • FSA available, including a lifestyle spending account subsidized by company
  • Employee discounts at hotspots

ReCode Therapeutics (www.recodetx.com) offers a competitive compensation/benefits package with a friendly, collaborative culture that values employee engagement and ongoing career development.

ReCode Therapeutics is an Equal Opportunity Employer.

Company

The Why Behind Our Work

We imagine a world where people living with genetic diseases can fully benefit from the promise of genetic medicines. Our novel mRNA and gene correction therapeutics have the potential to make this a reality.

Therapeutic Areas of Focus

Cystic fibrosis

Primary ciliary dyskinesia

Certain cancers and central nervous system (CNS) diseases

Power the Next Wave of Genetic Medicine

We are one of the rare companies whose innovations are poised to fundamentally shift an entire class of medicine.

Join us as we advance our pipeline into clinical development and scale ReCode’s next-generation genetic medicines delivery platform and pipeline.

Company info
Website
Phone
408-585-1700
Location
1140 O'Brien Drive
Menlo Park, CA 94025
US

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