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Scientist II, Pharmacology

Employer
AbbVie
Location
Lake County, Illinois
Start date
Feb 29, 2024

View more

Discipline
Science/R&D, Biotechnology, Pharmacology
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
BioMidwest, Best Places to Work

Job Details

AbbVie is a global, research-based biopharmaceutical company with a mission to develop innovative therapies to address the world's most complex and serious diseases. AbbVie employs approximately 47,000 people worldwide and markets medicines in more than 175 countries. The AbbVie portfolio consists of several marketed products in areas including Eye-care, Immunology, Oncology, Neuroscience, Virology, and Women’s Health as well as a pipeline containing multiple promising new molecules being studied in hundreds of clinical trials or advancing from Discovery into Development. AbbVie is a global organization with research sites in Boston (Worcester, MA), Chicago (North Chicago, IL), San Francisco Bay Area and in Germany (Ludwigshafen).

The Quantitative, Translational and ADME Sciences (QTAS) team at AbbVie, Inc. is seeking a Pharmacokinetic (PK) Analyst to join the Early PK and PK Logistics group at our corporate headquarters in the North Chicago, IL area.  The successful candidate will be responsible for designing pre-clinical animal PK studies and processing the data into viable report packages for project teams.  You will be expected to work closely with multiple key partners (i.e. QTAS project representatives, formulation scientists, pre-clinical safety, comparative medicine, etc.) to effectively and efficiently execute these pre-clinical studies. Applicants should have a strong foundational knowledge of pharmacokinetic principles and study design. The ideal candidate will preferably have some drug metabolism and pharmacokinetic (DMPK) background specifically with large molecule modalities such as: biologics, monoclonal antibodies, antibody drug conjugates, bispecific antibodies, gene therapy, etc.

Key Responsibilities:

  • Provide logistics support and primary responsibility to design, schedule, and execute pre-clinical animal studies across US-based research sites including PK, pharmacodynamic (PD), and toxicokinetic (TK) studies.
  • Process, analyze, and report pre-clinical animal PK data.
  • Interpret results through close partnership with cross-functional project representatives and support project teams across multiple therapeutic areas.
  • Collaborate with AbbVie’s Institutional Animal Care and Use Committee (IACUC) to align and implement industry leading standards for all pre-clinical animal studies.
  • Ability to effectively communicate and clearly articulate logistical and technical challenges across the organization.
  • Maintain excellent practices across all documentation platforms including electronic lab notebooks and analysis software.
  • Write, review, and contribute to pre-clinical study protocols and regulatory filing documents.

  • Qualifications: 

    Basic:

    • BS or equivalent education with typically 7 or more years of experience or MS or equivalent education with typically 5 or more years of experience.

    Preferred:

  • Background in pharmacokinetics and pharmaceutical sciences, especially with regards to large molecule modalities (biologics, monoclonal antibodies, antibody drug conjugates, bispecific antibodies, gene therapy, etc.)
  • Hands-on experience with pre-clinical animal study design and PK data analysis is preferred.
  • Experience with relevant analysis software, including Gastro Plus/PK Plus, Phoenix WinNonlin, Simcyp, etc. is a plus.
  • General understanding of in vitro and pre-clinical in vivo ADME/PK
  • Passion for data analysis, solving problems and applying new technologies to further scientific goals.
  • Proven ability to work in a team environment; ability to work well in a collaborative fast-paced team environment.
  • Demonstrated scientific writing skills and strong verbal communication skills.
  • Highly motivated, result-oriented person and independent thinker with proven ability to work cross-functionally and with other stakeholders.
  • Key Leadership Competencies:

  • Builds strong relationships with peers and cross-functionally with partners outside of team to enable higher performance.
  • Learns fast, grasps the "essence" and can change course quickly where indicated.
  • Raises the bar and is never satisfied with the status quo.
  • Creates a learning environment, open to suggestions and experimentation for improvement.
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality.
  •  

    Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 

    • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
    • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
    • This job is eligible to participate in our short-term incentive programs. 

    AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community, and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.


    Company

    AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, and YouTube.

    Stock Symbol: ABBV

    Stock Exchange: NYSE

    Company info
    Website
    Phone
    1-800-255-5162
    Location
    1 North Waukegan Road
    North Chicago
    Illinois
    60064
    US

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