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Sr. Scientist I, Systems Biology, Bioinformatics

Lake County, Illinois
Start date
Feb 24, 2024

Job Details

AbbVie’s Genomic Research Center (GRC) is seeking a highly-qualified Systems Biology scientist to join the Bioinformatics Genomic Sciences team at the GRC with a focus on developing computational Systems Biology capabilities for investigating complex biological systems across therapeutics and drug manufacturing. AbbVie’s GRC is a center of excellence for bioinformatics, functional genomics, and human genetics. The GRC works across all R&D including discovery and clinical development, supporting AbbVie’s numerous therapeutic areas, including science and technology, global epidemiology, search and evaluation, and corporate strategy.


We are seeking a talented and highly motivated computational scientist who will work on building and applying computational methodologies for understanding the interactions and dynamics of complex biological systems, especially applied to mammalian production cells to improve productivity and product quality of Biologics. This candidate will work collaboratively with bioprocessing, cell biology, and bioinformatics teams to develop computational models and gain insights into the underlying mechanisms of complex biological systems involved in the production of biologics. Strong communication and teamwork skills are essential as the candidate is expected to operate in a high-paced and multi-disciplined environment across geographic locations. This position will be on-site in Lake County, North Chicago.


Key Responsibilities:

·       Collaborate extensively and cross-functionally with both computational and bench scientists at the GRC and S&T Biologics in matrixed research environment to identify key factors and critical pathways that impact the production process and product quality.

·       Build computational Systems Biology capabilities, such as statistical models, algorithms, and simulations, and apply them to complex biological systems across therapeutics and drug manufacturing.

·       Manage, process, and analyze diverse sets of large-scale multi-omics data for investigating the underlying mechanisms of mammalian production cells.

·       Provide scientific leadership in designing experiments and developing innovative systems biology approaches to gain scientific understanding in the complex cellular processes.

·       Contribute to the development and validation of novel computational tools and methodologies for systems biology analysis in the field of bioprocessing.

·       Publish research findings, and present project designs and results clearly, both to individual stakeholders and at larger cross-functional scientific meetings and conferences.

·       Proactively seek out new information in the literature and incorporate this into individual project(s) as well as the overall program.

·       Maintain accurate records, documenting methodologies, and ensuring compliance with applicable regulations and quality guidelines.


·       Masters, or PhD in computational biology, bioinformatics, computer science, engineering, (bio)statistics, mathematics, or related fields with a focus on systems biology with typically 5+ (MS), or 0+ (PhD) years of experience.

·       Fluency in one or more relevant programming languages, such as R or Python, for performing custom computational analyses, executing existing algorithms, and developing novel software applications.

·       Experience working in an HPC Linux computing environment and familiarity with version control and deployment tools such as GitHub and Docker.

·       Ability to learn new skills and apply them in a fast-paced environment is a must.

·       Creativity, problem solving, and attention to detail are required.

·       Strong communication and collaboration skills are essential. Ability to work independently as well as in a team is a must.


Key AbbVie Competencies:

·       Builds strong relationships with peers and cross functionally with partners outside of the team to enable higher performance.

·       Learns fast, grasps the “essence”, and can change the course quickly where indicated.

·       Raises the bar and is never satisfied with the status quo.

·       Creates a learning environment, open to suggestions and experimentation for improvement.

·       Embraces the ideas of others, nurtures innovation and manages innovation to reality.

AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community, and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.


AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on Twitter, Facebook, Instagram, and YouTube.

Stock Symbol: ABBV

Stock Exchange: NYSE

Company info
1 North Waukegan Road
North Chicago

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