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Gene Editing, Intern

Employer
Life Edit Therapeutics
Location
Durham, NC
Start date
Feb 20, 2024

View more

Discipline
Clinical, Medical Writing, Science/R&D, Genetics
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Bio NC

Job Details

The Role: 

As an Intern at Life Edit Therapeutics, you will be part of a highly collaborative team focusing on advancing Life Edit’s RNA-guided editing systems as therapeutics. As part of the Gene Editing group, you will contribute to projects in the early discovery phase to characterize novel gene editing programs targeting diseases. A major goal is to transition these programs from research to preclinical development and eventually clinical advancement. The selected candidate will gain familiarity with various gene editing approaches and the experimental methodologies to evaluate them in vitro. 

Here’s What You’ll Do:  

    Perform routine mammalian cell culture to maintain various cell lines  Assist with the design and execution of experiments to assess new gene editing systems in different cell types, and perform troubleshooting when required  Critically analyze and summarize experimental data, while maintaining meticulous records of experimental methods and protocols  Follow current literature in the field of gene therapy and genome editing 

Requirements: 

    Candidates should be actively pursuing an undergraduate degree in Biology, Biochemistry, Molecular biology, or a related field. Research experience in a cell or molecular biology lab is desired Experience in tissue culture, including maintaining, transfecting, and performing  cell-based assays with mammalian cells (ex: flow-cytometry, cell proliferation and viability assays) is desired, but not required Understanding of molecular biology techniques (e.g. PCR, plasmid cloning, DNA/RNA extraction and purification, NGS library preparation, cDNA synthesis and RT-PCR, western blotting) Exceptional oral and written communication  

Why join Life Edit and the ElevateBio ecosystem?

Life Edit Therapeutics is an integrated subsidiary of ElevateBio, a technology-driven cell and gene therapy company that is accelerating access to the cutting-edge technologies and expertise that can change the future of medicine. Our integrated model combines multiple R&D technology platforms – including Life Edit gene editing – and cGMP manufacturing to power the discovery and development of advanced therapeutics. Our ecosystem is designed to enhance speed, delivery, and probability of success to change patient lives.

Life Edit is an integral part of ElevateBio’s ecosystem of platform technologies and is pioneering focused next-generation gene editing technologies and therapeutics. Located in Durham, NC, members of Life Edit work closely with the ElevateBio Research and Development and BaseCamp manufacturing teams in Waltham, MA. Life Edit is advancing therapeutic programs in collaboration with industry partners while building its own internal pipeline of gene editing therapies. We are looking for a unique individual who can continue to lead the cultural development of Life Edit and build on its momentum as an integral part of the ElevateBio ecosystem.

Our Mission:
To power the creation of life-transforming cell and gene therapies, at a speed the world deserves.

Our Vision:
We seek to be the world’s most indispensable cell and gene therapy technology company, redefining how companies operate, how products are created and how disease is treated.

ElevateBio is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. ElevateBio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Company

Life Edit Therapeutics is an ElevateBio company focused on advancing next-generation gene editing technologies and therapeutics. Life Edit has built a highly innovative platform with one of the world’s largest and most diverse libraries of RNA-guided nucleases (RGNs), base editors, and reverse transcriptase (RT) editors that provide flexible editing and unprecedented access to the genome. The platform allows Life Edit to target any genomic sequence and potentially develop novel human therapeutics for the most challenging genetic diseases by enabling ex vivo engineering for cell therapies and regenerative medicines and in vivo delivery of gene therapies.

Company info
Website
Location
300 Morris Street, Suite 300
Durham
NC
27701
United States

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