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Process Development Senior Scientist HTE Solid State / Crystallization (Synthetics)

Thousand Oaks, California
Start date
Feb 18, 2024

Job Details


Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Process Development Senior Scientist HTE Solid State / Crystallization



What you will do

Lets do this. Lets change the world. Amgen is currently seeking a dedicated Process Development Senior Scientist to join our High-Throughput Experimentation (HTE) & Automation group in Drug Substance Technologies Synthetics (DSTS) at Thousand Oaks, CA. Amgens DSTS group within Process Development (PD) organization is responsible for the invention and development of drug substance manufacturing processes and technologies to advance Amgen's exciting portfolio of synthetic and hybrid assets. Process chemists/chemical engineers within the HTE & Automation group support high throughput screening activities, including polymorph screening, salt screening, solubility measurements and solid-state characterization, and assist drug substance teams with the development of robust crystallization processes. The successful candidate will be a highly motivated and team-oriented individual with a strong background in chemical engineering and/or chemistry with a consistent track record of scientific innovation and achievement.

Scientific/Technical Responsibilities
  • Design and perform high-throughput polymorph screening, salt screening, solubility measurements and solid-state characterization of drug substance intermediates.
  • Develop crystallization processes for active pharmaceutical ingredients (API) and drug substance intermediates that optimize quality, physical properties, morphology and particle size distribution.
  • Support cGMP manufacturing and technology transfer to our internal manufacturing facilities and external contract manufacturers.
  • Advance digital and automation technology to support high-throughput workflows and enhanced crystallization development.
  • Serve as a technical expert and keep current in the field of solid form science and crystallization engineering.
  • Actively contribute to drug substance development teams by providing project updates, data interpretation, and technical recommendations.
  • Maintain good laboratory documentation practices and compliance with electronic laboratory notebook (ELN) guidelines.
  • Work effectively in a multi-disciplinary team of chemists, engineers and attribute scientists.
  • Work independently in advancing projects and studies within required deadlines.


What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The scientific professional we seek will possess these qualifications.

Basic Qualifications:

Doctorate degree PhD OR PharmD OR MD in Chemical Engineering or Chemistry completed by June 2024


Masters degree in Chemical Engineering or Chemistry and 3 years of industry experience


Bachelors degree in Chemical Engineering or Chemistry and 5 years of industry experience

Preferred Qualifications:
  • Ph.D in chemical engineering with a specialization in solid form science and/or crystallization engineering
  • Demonstrated ability to conduct independent research
  • Experience in solidstate techniques (DSC, TGA, XRD, PLM, DVS, particle characterization, Raman, IR, etc.)
  • Experience with automation systems (e.g., Unchained Labs, Chemspeed, Chronect, etc.) and data visualization software (e.g., Spotfire)
  • Excellent communication skills (both written and oral) and the ability to work well in teams


What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates professional and personal growth and well-being.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans and bi-annual company-wide shutdowns
  • Flexible work models, including remote work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.


We are all different, yet we have this in common: our mission to serve patients. This sense of shared purpose is key to our becoming one of the world’s leading biotechnology companies. It guides us as we continue to launch new medicines and reach millions of patients worldwide.

We live the mission.

We win together.

We thrive on continual challenge.

Our team of 22,000+ scientists and professionals worldwide bring distinct perspectives and experiences to all we do. We leverage our global talent to achieve together—to research, manufacture and deliver ever-better products and greater depth to our mission.

At Amgen, there is a strong correlation between our high level of diversity and performance. Because addressing issues with a wider range of perspectives and approaches leads to more creative problem-solving. Together, we’re transforming the promise of science and biotechnology into therapies that have the power to restore health.

Connect with us to explore how you can Win, Live, and Thrive at Amgen.

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Company info
Corporate Headquarters
One Amgen Center Drive
Thousand Oaks
United States

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