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Graduate Intern

Employer
Barinthus Biotherapeutics
Location
Germantown, MD
Start date
Feb 13, 2024

View more

Discipline
Science/R&D, Bio-Assay Development, Biology, Immunology, Laboratory
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
BioCapital

Job Details

Barinthus Biotherapeutics is a fast-growing biotech company headquartered in Harwell, UK, and listed on Nasdaq in the United States. At only seven years old we already have a development portfolio of nine programmes, a partnered product that is in commercial production which has seen more than 3 billion doses administered worldwide and an IPO behind us. We are a publicly-listed clinical stage biopharmaceutical company that spun out of the University of Oxford’s Jenner Institute, one of the most prestigious vaccine research centres in the world. We discover and develop immunotherapeutics for the treatment and prevention of infectious diseases, autoimmune diseases and cancer. Our achievements include co-inventing and jointly developing our COVID-19 vaccine, Vaxzevria, which we assigned to Oxford University Innovation to facilitate the licensing of those rights to AstraZeneca. We have ongoing clinical studies exploring treatments for patients with HBV, HPV and prostate cancer, and have pre-clinical programs in coeliac disease and HPV cancer. We conduct research globally and have ambitious plans in the UK and US, where we will continue to grow our teams over the coming months and years.

About the position

This position will be responsible for conducting immunological assays to support the preclinical research and development activities for immunotherapies as part of a multi-disciplinary team of chemists, immunologists, and engineers. The position will also provide support for candidates to plan, execute and analyze immunoassays. The primary focus for the successful candidate will be the assessment of immune responses elicited via immunotherapies with autoimmune, cancer or other antigens targets using our SNAP platform. Data collection will require the use of flow cytometry and other immune technologies. The resulting data will help guide the development of vaccines for the treatment of cancer and autoimmune diseases. The role will be primarily laboratory-based, but there will be opportunities for planning, presentation, and strategy with acquired experience.

 

Key responsibilities include

  • Perform preclinical studies to include coordinating with CROs, processing of blood and tissue samples, flow cytometry, ELISAs, data acquisition
  • Analyze acquired data, synthesize findings, and recommend next steps in regular written and oral presentations
  • Manage and organize immunology/biology lab inventories, instrumentation, and spaces
  • Work with the research team to help design research studies in animal models and in vitro to identify promising formulations for advancement to lead development.
  • Interface with the chemistry team to set priorities for synthesis and testing of candidate immunotherapies

 

Essential knowledge, experience, and skills

  • BS or MS in immunology, biology, or related discipline
  • Lab experience in the conduct of immunological assays, preferably including:
    • Preparation of immune cells from animal or human tissues and cell cultures
    • Flow cytometry (staining, collection, and analysis)
    • Cell culture
    • ELISAs (preferred)
  • The ability to work collaboratively in a dynamic team environment
  • Experience using SOPs and operating under quality systems
  • Experience in data management, analysis, and presentation

Notice to recruiters

 

Barinthus Biotherapeutics' internal Talent Acquisition leads recruitment and employment for Barinthus Biotherapeutics. Unsolicited resumes sent to Barinthus Biotherapeutics from recruiters do not constitute any type of relationship between the recruiter and Barinthus Biotherapeutics and do not obligate Barinthus Biotherapeutics to pay fees should we hire from those resumes. Barinthus Biotherapeutics operate a preferred list of recruitment suppliers, any and all equiries about joining us as a supplier should be directed to Barinthus Biotherapeutics' TA Team. We ask that external recruiters and/ or agencies not contact or present candidates directly to our hiring manager or employees.

Company

Barinthus Biotherapeutics plc is a clinical-stage biopharmaceutical company developing novel T cell immunotherapeutics that guide the immune system to overcome chronic infectious diseases, autoimmunity and cancer. The company stands apart through its broad pipeline, built around four proprietary platform technologies;ChAdOx, MVA, SNAP-TI and SNAP-CI. These platforms are enabling the company to develop antigen-specific immunotherapeutics that aim to optimize the disease-fighting capabilities of T cells and guide them towards a healthy balance. Leading the way with a passion for science embodies everything we do at Barinthus Biotherapeutics – even our new name. Barinthus was the name of the mythological navigator who guided the legendary King Arthur of Britain by ship to the island of Avalon to be healed after he was wounded. Like Barinthus, our company aims to be a strong and resilient guide, navigating those that rely on us toward better health. In this most important journey, our vessel is the power of science and our expertise to harness it in directing the immune system to help people overcome chronic infectious diseases, autoimmunity, and cancer. While our eyes are keenly focused on moving science forward, we also draw inspiration from the past. Aligning the name of our company with an Arthurian legend is a nod to our rich UK-based history as a dedicated steward of science and unwavering champion of patients. If the past is prologue for the future, then we proudly embrace the values and technological approach that continue to be the hallmark and fabric of our company – now more than ever as we blaze on as Barinthus Biotherapeutics.
 

Company info
Website
Phone
+441865591439
Location
20400 Century Blvd
Germantown
Maryland
United States

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