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Process Development Senior Scientist - Drug Substance Technologies Synthetics

Thousand Oaks, California
Start date
Feb 10, 2024

Job Details


Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Process Development Senior Scientist - Drug Substance TechnologiesSynthetics


What you will do

Amgen is currently seeking a talented Process Development Senior Scientist to join our Drug Substance Technologies - Synthetics (DSTS) group at Thousand Oaks, CA. Amgens DSTS group within Process Development (PD) is responsible for the invention and development of drug substance manufacturing processes and technologies to advance Amgen's exciting portfolio of synthetic and hybrid assets. Process chemists within our team apply their synthetic training to invent synthetic routes and chemical processes to support drug substance manufacturing from early to late-stage development. The successful candidate will be a highly motivated and team-oriented individual with a strong background in organic chemistry and/or biochemistry with a track record of scientific innovation and achievement.

Key Responsibilities:
  • Invent synthetic routes and develop safe, robust, and cost-effective processes to manufacture synthetic and hybrid drug substances
  • Advance enabling technologies to accelerate pharmaceutical development and to improve sustainability and process efficiency, including advances in biocatalysis, high-throughput technology, flow chemistry, and AI/machine learning
  • Support cGMP manufacturing and technology transfer to our internal manufacturing facilities and external contract manufacturers
  • Ensure process performance through process understanding, modeling and characterization
  • Contribute to drug substance development teams by providing experimental results, technical updates, documentation, data interpretation, recommendations, etc.
  • Work cross-functionally to deliver regulatory documents and support regulatory filings
  • Serve as a technical expert and keep current in the field of organic and process chemistry
  • Work effectively in a multi-disciplinary team of chemists, engineers and attribute scientists
  • Be able to work independently to drive results and advance projects


What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The self-starter professional we seek is a scientist with these qualifications.

Basic Qualifications:

Doctorate degree in Chemistry completed by June 2024


Masters degree in Chemistry and 4 years of industry experience


Bachelors degree in Chemistry and 6 years of industry experience

Preferred Qualifications:
  • Doctorate degree in organic chemistry or biochemistry with a specialization in biocatalysis, oligonucleotide chemistry, synthetic/conjugation chemistry and/or chemoinformatics/machine learning
  • Post-doctoral experience in an academic laboratory or pharmaceutical/biotech industry
  • Track record of peer-reviewed publications and research presentations
  • Ability to work within a dynamic and interdisciplinary environment to achieve results
  • Excellent written and verbal communication, ability to multitask, effectively plan and follow through on complex projects
  • A research summary included with CV is strongly encouraged


What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates professional and personal growth and well-being.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans and bi-annual company-wide shutdowns
  • Flexible work models, including remote work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.


We are all different, yet we have this in common: our mission to serve patients. This sense of shared purpose is key to our becoming one of the world’s leading biotechnology companies. It guides us as we continue to launch new medicines and reach millions of patients worldwide.

We live the mission.

We win together.

We thrive on continual challenge.

Our team of 22,000+ scientists and professionals worldwide bring distinct perspectives and experiences to all we do. We leverage our global talent to achieve together—to research, manufacture and deliver ever-better products and greater depth to our mission.

At Amgen, there is a strong correlation between our high level of diversity and performance. Because addressing issues with a wider range of perspectives and approaches leads to more creative problem-solving. Together, we’re transforming the promise of science and biotechnology into therapies that have the power to restore health.

Connect with us to explore how you can Win, Live, and Thrive at Amgen.

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Company info
Corporate Headquarters
One Amgen Center Drive
Thousand Oaks
United States

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