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Senior Scientist - Cardiometabolic Disorders

Thousand Oaks, California
Start date
Feb 2, 2024

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Science/R&D, Biotechnology
Required Education
Bachelors Degree
Position Type
Full time
Biotech Beach, Best Places to Work

Job Details


Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Senior Scientist


What you will do

Lets do this. Lets change the world. The Department of Cardiometabolic Disorders at AMGEN Inc. is currently seeking a dedicated scientist to contribute to our research efforts in developing new treatments for cardiometabolic diseases. This role requires a commitment to developing a deep understanding of the pathogenic mechanisms that underlie obesity. In this vital role, you will be driving discovery efforts to identify how Amgens innovative biological modalities can improve the lives of patients who suffer from heart failure and related co-morbidities.

Key Responsibilities:
  • Identification of new therapeutic targets and preclinical validation. The candidate is expected to be continuously aware of scientific developments in cardiometabolic disease, with an emphasis on obesity.

  • Work collaboratively with a team of expert cardiometabolic scientists.

  • Present research discoveries to AMGEN colleagues and scientific meetings (oral or poster presentations and publish scientific papers in peer-reviewed journals).

  • Lead ethical, high-quality research experiments in accordance with regulatory agencies and compliance guidelines.

  • Design or assist in the development of medium to low-throughput assays used to support both small and large molecule drug development programs.

  • Design and implement in vitro, ex vivo. It is critical that the candidate is familiar with the pathophysiology of heart diseases and related co-morbidities.

  • Independently design, perform, and analyze laboratory experiments, including troubleshooting, optimization of assays, data collection, interpretation, biostatistical analysis, and presentation.

  • Participation in cross-functional drug development teams as a key intellectual and technical contributor.

  • Function optimally in a team-based or collaborative environment as part of a highly integrated team, possess excellent organizational, verbal, and written communication skills, and demonstrate the ability to produce reliable and reproducible results.


What we expect of you

We are all different, yet we all use our outstanding contributions to serve patients. The senior scientist we seek is technically adept with these qualifications.

Basic Qualifications:
  • Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable]

  • Masters degree and 3 years of relevant experience OR

  • Bachelors degree and 5 years of relevant experience

Preferred Qualifications:
  • PhD with a degree in biology or a related discipline.

  • 5 or more years of experience in cardiometabolic research in industry or academic settings.

  • Willing to work in a team environment and possess good laboratory documentation skills.

  • Postdoctoral research experience.

  • Ability to perform in vitro assays to dissect the mechanism of action of therapeutic molecules in cardiac myocytes, fibroblasts, adipocytes, endothelial cells, and other relevant cardiac cell types.

  • In vitro experience with cultured cell lines, siRNA transfection techniques, western blotting, quantitative PCR techniques, RNA/DNA isolation, laboratory automation, high-content imaging technology, and fluorescence microscopy.


What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates professional and personal growth and well-being.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

  • Stock-based long-term incentives

  • Award-winning time-off plans and bi-annual company-wide shutdowns

  • Flexible work models, including remote work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us!

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.


We are all different, yet we have this in common: our mission to serve patients. This sense of shared purpose is key to our becoming one of the world’s leading biotechnology companies. It guides us as we continue to launch new medicines and reach millions of patients worldwide.

We live the mission.

We win together.

We thrive on continual challenge.

Our team of 22,000+ scientists and professionals worldwide bring distinct perspectives and experiences to all we do. We leverage our global talent to achieve together—to research, manufacture and deliver ever-better products and greater depth to our mission.

At Amgen, there is a strong correlation between our high level of diversity and performance. Because addressing issues with a wider range of perspectives and approaches leads to more creative problem-solving. Together, we’re transforming the promise of science and biotechnology into therapies that have the power to restore health.

Connect with us to explore how you can Win, Live, and Thrive at Amgen.

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Company info
Corporate Headquarters
One Amgen Center Drive
Thousand Oaks

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