This job has expired

You will need to login before you can apply for a job.

Investigator I/II

Employer
CSL Behring
Location
Massachusetts
Start date
Dec 7, 2023

View more

Job Details

Job Description

The Opportunity:

The prospective Investigator will lead the efforts to optimize lipid nanoparticles (LNP) with propriety lipid from CSL Seqirus. The successful candidate will be expected to lead the new LNP process development and play a significant role in cross functional collaborations with biochemistry, molecular & cell biology and analytical development teams. You will provide scientific expertise for LNP formulation process and mentor junior scientists.

The Role:

  • Lead the design and execution of experiments to validate and optimize LNPs

  • Design and execute Design of Experiment (DOE) principles in formulation screening activities

  • Work on medium to high throughput formulation preparation

  • Work with Automation, Chemistry, and other colleagues to validate and implement LNPs

  • Collaborate with various pre-clinical groups to support advancement of LNP products

  • May lead technical project team with cross functional members

  • Support development/optimization of LNP characterization

  • Author study protocols, development and characterization reports, as well as scientific manuscripts for external publication

  • Present results and findings at internal and external meetings

  • Provide guidance to junior team members, interns, and act as a resource for colleagues with less experience

Skills & Experience:

  • Minimum of 1 years' relevant industry experience and /or equivalent experience in a relevant academic environment.

  • PhD in engineering, biochemistry, chemistry, biology or related fields with pharmaceutical industry experience (1-7 years PhD)

  • Familiar with the LNP process (LNP formation through mixing, Tangential Flow Filtration (TFF), and sterile filtration)

  • Strong expertise in the design and development of lipid nanoparticles for oligonucleotide delivery

  • Demonstrated expertise in formulation screening design

  • Understanding of physical and chemical degradation mechanism for mRNA and LNPs

  • Effective verbal & written communication skills in a cross functional environment

About Us

Our Benefits

Seqirus is committed to attracting and retaining world-class employees who are valued for their contributions to achieving business objectives. Learn more about some of the benefits you can participate in when you join Seqirus.

About Seqirus

Seqirus is part of CSL Limited (ASX: CSL). As one of the largest influenza vaccine providers in the world, Seqirus is a major contributor to the prevention of influenza globally and a transcontinental partner in pandemic preparedness. Learn more about Seqirus.

We want Seqirus to reflect the world around us

As a global organisation with employees in 35+ countries, CSL embraces diversity, equity and inclusion. Learn more about Diversity, Equity & Inclusion at Seqirus.

Do work that matters at Seqirus!

Company

As the third largest global biotechnology company with employees in more than 35 countries, CSL Behring is focused on serving patients with serious and rare diseases, including coagulation disorders, primary immune deficiencies, hereditary angioedema, respiratory disease and neurological disorders. We collaborate with patient and biomedical communities to improve access to therapies, advance scientific knowledge and support future medical research. 


CSL Behring's dynamic environment fosters innovation and attracts the best and brightest who share a commitment to helping save lives. People here are free to live their Promising FUTURES where they can fulfill their individual career aspirations and realize their potential. 


CSL Behring is committed to diversity and inclusion, both of which underpin our Values of patient focus, innovation, collaboration, integrity and superior performance. We believe that by harnessing and honoring the unique capabilities, experiences and perspectives of our people, we are better able to serve our patients.


CSL Behring operates one of the world's largest plasma collection networks, CSL Plasma. The parent company, CSL Limited, headquartered in Melbourne, Australia, employs more than 27,000 people, and provides its life-saving medicines in more than 70 countries. 
For more information visit www.cslbehring.com. Help us deliver on our promise to save lives and protect the health of people around the world. Promising FUTURES start at CSL Behring!

Stock Symbol: CSL

Stock Exchange: Australian Securities Exchange

Company info
Telephone
610-878-4000
Location
1020 First Avenue
King of Prussia
Pennsylvania
19406
United States

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert