Who We Are
From research and discovery to post-market clinical development, our WWRD engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with genetic diseases.
BioMarin’s Research & Development group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with genetic diseases. Come join our team and make a meaningful impact on patients’ lives.
Genetics and Genomics are one of the key pillars on all BioMarin programs. The Genomics team within Research & Early Development (RED) is a key partner on BioMarin therapeutic programs at all stages of the pipeline. We are seeking a Scientist 1 or 2 to join the discovery omics team to support early drug discovery and research efforts at BioMarin.
The successful candidate will have the opportunity to contribute to or lead diverse efforts such as identification of regulatory and potentially disease-modifying targets as well as molecular characterization of human disease and disease models. This is an opportunity to work with dynamic, cross-functional teams where you can apply your expertise in bioinformatics and satisfy your curiosity in human biology and molecular mechanisms. You can get directly involved in the discovery and development of the next generation of therapeutics (e.g., gene therapy and oligonucleotides), and collaborate with experts across a wide range of disease domains (neuro, cardiovascular, musculoskeletal, non-oncology hematology). Most importantly, you will have a chance for your work to have immediate impact on a fast-moving drug discovery and development process, to improve the lives of patients.Responsibilities:
- Analyze and integrate omics data to drive disease understanding, disease model characterization, target identification, and molecular characterization.
- Develop and apply methods to identify new regulatory mechanisms, particularly at the RNA level, which we can target to treat genetic diseases.
- Communicate discoveries to internal colleagues with a variety of backgrounds and to the wider scientific community through presentations and publications.
- Collaborate to empower colleagues in Functional Genomics, Clinical Genomics, and Statistical Genetics, and our partners in the therapeutic areas.
- Evaluate and develop bioinformatics methods to analyze and integrate omics data and report results. Examples include RNA-seq, single cell RNA-seq, long read RNA-seq and CUT&RUN data.
- PhD in computational biology, bioinformatics, biology, or related fields.
- Hands-on experience to manage, analyze and interpret large omics datasets, particularly transcriptomics data.
- Strong computational abilities and fluency in at least one major programming language (ideally Python or R).
- Desired: Background in molecular biology, particularly RNA biology, or a strong interest in these fields.
- PhD or equivalent relevant experience, plus 0-2+ years industry experience
- PhD or equivalent relevant experience plus 2-5+ years industry experience
Hybrid requires an onsite presence 2x weekly at our San Rafael, CA location. (zip 94901)
Role is virtual if you live 100+ miles from our San Rafael, CA location. (zip 94901)
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, sexual orientation, national origin, disability status, protected veteran status, or any other characteristic protected by law.