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Cell Therapy Innovation Internship - Summer 2024

Employer
Takeda
Location
Boston, Massachusetts
Start date
Dec 1, 2023

View more

Discipline
Science/R&D, Biotherapeutics
Required Education
Doctorate/PHD/MD
Position Type
Full time
Hotbed
Genetown, Best Places to Work

Job Details

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

At Takeda, we strive to create an exceptional people experience for patients, communities, partners, and employees. As a patient-focused, values-based, R&D-driven global biopharmaceutical company, we know our decisions and actions affect people’s lives. We look to our values of Takeda-ism, which incorporates Integrity, Fairness, Honesty and Perseverance, and Patient-Trust-Reputation-Business as a guide in our decision-making process to ensure we do what’s right – for our patients, our people and society.

Are you ready to embark on a transformative journey with Takeda? Our paid 10–12-week summer internship program is designed to immerse you in a dynamic learning environment, featuring a blend of developmental and social activities.

As a Takeda intern, you'll have the opportunity to contribute to impactful projects that play a crucial role in shaping both our business and the well-being of patients. This experience will not only allow you to apply your technical and business knowledge but also empower you to showcase your analytical strength and creative problem-solving skills.

Seize this chance to gain hands-on experience, expand your skill set, and make a meaningful impact on the healthcare industry. We invite you to be a part of our innovative and collaborative team, where your contributions matter.

For more information about Takeda, please visit www.takeda.com. op of Form

Please note that Takeda does not provide intern housing or a housing stipend.

Project Outline:

The intern will be working on evaluating the effect of Lenalidomide, an IKAROS inhibitor in enhancing CAR-Vδ1 T cell functions. The specific studies will include:

  • Examine if Lenalidomide, an IKAROS inhibitor and FDA-approved immunomodulatory small molecule, can improve the cytotoxicity, cytokine secretion and persistence of CAR-Vδ1 T cells.

  • Using RNA-seq and ATAC-seq to analyze gene expression and epigenetic changes in CAR-Vδ1 T cells with or without Lenalidomide treatment.

  • Test additional genetic approaches such as shRNA/KD to modulate IKAROS expression in CAR-Vδ1 T cells and the feasibility to incorporate into CAR-Vd1 T cell products.

This position is fully on-site.

How you will contribute:
  • Exceptional interpersonal, verbal communication and writing skills.

  • Deadline-driven with an elevated level of organizational and planning skills.

  • Strong quantitative, analytical, problem solving and conceptual skills.

  • Proven record of accomplishment of teamwork, adaptability, innovation, initiative, and integrity.

  • Global mindset to grow in a diverse work environment.

Requirements / Qualifications:
  • Currently authorized to work in the US (United States) without sponsorship. Takeda does not provide sponsorship for internship positions.

  • Available to work full-time (40 hours/week), within the core business hours of 8:00am – 5:00pm, for 12 weeks during the summer months.

  • Graduate, PhD, MD student with completion of a minimum of one year of university studies.

  • Must be enrolled in school the semester following your internship with Takeda.

  • Experience with immunology, cell biology and/or molecular biology strongly preferred.

  • Hands-on experience with mammalian cell culture required. Previous experience with primary human immune cell culture preferred.

  • Previous working experience with gene editing, RNA-seq and ATAC-seq is a plus.

  • Please note that Takeda does not provide intern housing or a housing stipend.

The hourly pay rate range is $20.00 per hour - $46.00 per hour. The final pay rate offered for this internship may consider several factors including, but not limited to, location, skills, education, and experience.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Paid Intern (Fixed Term) (Trainee)

Time Type

Full time

Company

Takeda is a global, values-based, R&D-driven biopharmaceutical leader headquartered in Japan, committed to discover and deliver life-transforming treatments, guided by our commitment to patients, our people and the planet. Takeda focuses its R&D efforts on four therapeutic areas: Oncology, Rare Genetics and Hematology, Neuroscience, and Gastroenterology (GI). We also make targeted R&D investments in Plasma-Derived Therapies and Vaccines. We are focusing on developing highly innovative medicines that contribute to making a difference in people’s lives by advancing the frontier of new treatment options and leveraging our enhanced collaborative R&D engine and capabilities to create a robust, modality-diverse pipeline. Our employees are committed to improving quality of life for patients and to working with our partners in health care in approximately 80 countries and regions.

For more information, visit https://www.takeda.com.

Stock Symbol: TAK

Company info
Website
Location
650 East Kendall Street
Cambridge
MA
02421
United States

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