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Principal Engineer/Senior Principal Engineer, Global MS&T- Cell Therapy

Employer
Bristol Myers Squibb Company
Location
Seattle, Washington
Start date
Dec 1, 2023

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Discipline
Science/R&D, Biotherapeutics
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Best Places to Work

Job Details

Working with Us
Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. Youll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Cell Therapy is one of the most groundbreaking new forms of cancer treatments being studied today. With therapies only in their infancy and BMSs continued investment in our Cell Therapy capabilities, the growth potential of this science, your career, and the ability to help patients are incredible.

Position Summary

Come, join the BMS Cell Therapy Development and Operations (CTDO) Division, and be a part of the team building leading cell therapy platforms to serve our patients with novel cellular immunotherapies. The Viral Vector Commercial Network Manufacturing Science and Technology (MS&T) group plays a critical role in technology transfers, process validation, CMC life cycle management, technical oversight of external manufacturing partners, process engineering and establishing manufacturing standards to enable a robust and scalable global cell therapy manufacturing network.

We are looking for a Principal Engineer/Senior Principal Engineer to join our Viral Vector Commercial Network MS&T group. The primary responsibility will be commercial manufacturing support of our CMO GMP manufacturing facilities. Additional responsibilities include Implementation of operational improvements and resolving manufacturing process investigations. The engineer will be part of a team tasked with determining the root cause of manufacturing investigations. Additionally, the engineer will write technical reports in support of manufacturing process changes, optimizations, and regulatory filings. Optimizing the manufacturing process and determining root cause of manufacturing deviations are critical to ensure sufficient capacity to support clinical and commercial manufacturing.

In addition to commercial manufacturing support, the successful candidate will be part of a team responsible for transferring commercial manufacturing processes. The candidate will play a key role in product lifecycle management, including strategic development, validation, and approval of viral vector products. This person will collaborate across functional teams to insure project advancement, rapid and best in class execution, and communication of challenges/opportunities.

Additionally, the candidate will write technical reports in support of manufacturing process changes, deviation investigations and regulatory filings. s, etc.), training of personnel, and support of PPQ strategies and commercial manufacturing. This position may have direct reports and report to the Associate Director of Vector and Gene Deliver MS&T Seattle, WA

Key Responsibilities

  • Support all MSAT activities at CMOs to ensure uninterrupted clinical/commercial vector manufacturing and supply.
  • Provide technical process support for routine clinical/commercial batches and assist QA with on time closure of all quality system records such as deviations, CAPAs and change controls.
  • Develop, understand, and manage tools/templates to monitor vector manufacturing process performance and enable understanding of process capability.
  • Implement and support the execution of process control strategies including execution of process risk assessments, and CPV.
  • Ensure the manufacturing process is in a state of control, through an understanding of CPV data.
  • Support production related investigations, ensuring compliance with internal standards and regulatory requirements.
  • Leverage and maintain strong relationships with external CMOs and their vendors.
  • Support permanent inspection readiness and actively support regulatory inspections.
  • harmonized across the cell therapy manufacturing network.
  • Develop, execute manufacturing process improvement activities in accordance with the overall life cycle plan for the product.
  • Share operational best practices and process learning with the rest of the manufacturing network.

Qualifications & Experience

  • Biochemical, Chemical, Biomedical Engineering or Cell Biology/Immunology discipline with
    • B.S. with 10-14 years of relevant experience
    • M.S with 8-12 years of relevant experience
    • Ph.D. with 4-8 years of relevant experience
    • Experience level will determine position title and enterprise grade level.
  • Experience with cellular therapies is desired but not required.
  • Experience should include technical support of a cGMP manufacturing facility, including strong knowledge and engineering leadership for viral vector manufacturing and processing equipment, manufacturing support and technology transfer.
  • Flexibility to work within manufacturing schedules and ability to travel frequently (50%).
  • Ability to work in a self-driven, performance/results oriented, fast paced matrix environment Excellent communication, writing, sense of urgency, teamwork, and presentation skills.
  • Strong interpersonal skills required to work with teams in different functions and organizations.
  • Demonstrated ability to effectively work in cross functional teams, meet deadlines, and prioritize multiple projects.
  • Proficiency utilizing MS Office products and working knowledge of statistical software (R, JMP, Minitab) strongly suggested.
  • Detail oriented with excellent verbal and written communication skills.

The starting compensation for this job is a range from $114,000-$163,000 plus incentive cash and stock opportunities (based on eligibility).

The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed.

Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our website https://careers.bms.com/working-with-us

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Years holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

BMSCART

If you come across a role that intrigues you but doesnt perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as Transforming patients lives through science , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol
Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Company

Bristol Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.

At Bristol Myers Squibb, we believe in the power of science to address some of the most challenging diseases of our time. Our focus on these unmet needs comes during a remarkable time, when unprecedented scientific breakthroughs are advancing the treatment of disease as never before in human history.

We work every day to transform patients’ lives through science. Each day, our employees around the world work together for patients – they are at the center of everything we do. They inspire us. They are the reason we come to work each day.

We combine the agility of a biotech with the reach and resources of an established pharmaceutical company to create a global leading biopharma company powered by talented individuals who drive scientific innovation.

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Company info
Website
Phone
+1-800-332-2056
Location
430 E. 29th St
14th Floor
New York
New York
10016
United States

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