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Scientist II - Global Drug Discovery-Immunobiology

Novo Nordisk
Lexington, MA
Start date
Nov 28, 2023

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Science/R&D, Biotechnology, Pharmacology
Required Education
Bachelors Degree
Position Type
Full time
Genetown, Best Places to Work

Job Details

About the Department

Our Boston Research & Development hub, anchored in the greater Boston area, brings together the best minds in life science innovation. The teams located in facilities in Lexington, Watertown and Cambridge reflect the full R&D continuum, from early research through late-stage clinical development. Here, we are building for the future, creating a distinct R&D community based on collaboration, partnerships, and cutting-edge research across multiple modalities and therapeutic areas. We recognize that improving human health starts here and that patients rely on us. Our greater Boston R&D hub merges biotech speed and agility with large pharmaceutical company quality, resources, and stability, uniting the best of both worlds to develop new medicines for patients

Our vision is to be at the forefront of neurobiology, leading the charge in pushing the boundaries of scientific knowledge and pharmaceutical advancements. We aspire to be recognized globally and locally as a hub of creativity, innovation, and collaboration, where ideation and discovery flourish. By integrating exploratory technology, in vitro models, and state-of-the-art brain delivery systems, we strive to deepen our understanding of the mechanisms underlying brain function and dysfunction within our focus areas obesity and cardiometabolic disease. Through close collaboration with in vivo researchers and chemists, we endeavor to translate our findings into novel, effective treatments that can reshape the landscape of obesity management. With a focus on driving our pipeline forward and embracing outsourcing models and external collaborations, we are poised to make significant contributions to impact human health by advancing the frontiers of neuroscience research.


The Position

The Scientist II will provide subject matter expertise and leadership in the expansion of biology and disease understanding; identification and validation of new drug targets; advancing novel therapies to the clinic; and developing technologies to accelerate scientific research. This will be achieved by coordinating multiple research activities involving cross-functional project teams to ensure achievement of key deliverables. The Scientist II will represent the organization to the external scientific community through publication and presentation of research, and through the development, management, and leadership of external collaborations. The individual will be seen across the company as a method/subject expert for immune mechanisms related to cardiometabolic and rare diseases, and for core technologies like flow cytometry.



Reports to the head of the Immunobiology department. Internal relationships include working closely with colleagues at US, UK, Denmark, and China research sites to support the Global Drug Discovery pipeline. The Scientist II will have regular cross-functional, global collaborations with both internal teams and external partners. This individual may supervise contingent workers and mentor others in their functional area. Individual will interact with external research collaborators both academia & industry-based.


Essential Functions

  • Major contributor to research projects through hands-on independent work involving highly complex activities, receiving minimal guidance
  • Leads research projects (target, biology, or technology-related) involving coordination of multiple experimental activities and groups, recommends and is responsible for ensuring realistic project timelines and deliverables, and works closely with local or global project managers
  • Influences the research pipeline by recommending, presenting, and championing new targets or methodologies; proposing and leading external collaborations; and makes project activity-related decisions
  • Demonstrates subject matter expertise and in-depth experience, as well as creative, independent thinking to identify and address disease/biology-related questions/gaps, potentially across therapeutic areas
  • Analyzes complex data with high degree of sophistication, connecting disparate datasets to reach conclusions, and set direction on experiments. Authors internal reports and external publications
  • Effectively communicates and collaborates across global sites and guides project strategy by providing expert input to cross-functional project teams
  • Represents the organization at scientific conferences and global meetings by authorship and publication of scientific papers and patents
  • Maintains a strong understanding of advancements in their area of expertise
  • Participates to or leads cross-functional experimental teams to achieve project goals, mentor junior staff, and provide training. Acts as a resource for colleagues with less experience; may direct the work of other staff members
  • Works with Department Heads and Scientists to ensure better practice sharing and implementation within the research environment
  • Demonstrates superior cross-cultural understanding to effectively interact with relevant stakeholders in the global organization
  • Be an active contributor to creating and sustaining an inclusive culture of curiosity that embraces diversity



  • Bachelor 's Degree within subject matter expertise required
  • With Bachelor’s Degree, 15+ years’ relevant experience required; a master’s degree with 10+ years’ relevant experience, or a Doctoral degree in with 4+ years’ post-doctoral and/or industry relevant experience can be considered
  • Demonstrates excellent verbal and written communication skills
  • Demonstrates outstanding project management knowledge, as well as organizational and time-management skills
  • Required experience:
  • Expertise in field of immunology (human and rodent) – subject matter expertise in fibrogenesis, innate/adaptive regulatory mechanisms, immunometabolism, immune aging and senescence, cytokine regulation, or myeloid biology considered
  • Expertise in flow cytometry panel design & analyses, flow- & electrochemiluminescence-based cytokine measurements, cytotoxicity assay development, & live cell imaging
  • Experience in developing & optimizing highly complex multi-cellular assays
  • Experience working with human blood & tissue
  • Expert cell culture skills – human, rodent, non-human primate
  • Knowledge of cardiometabolic disease, especially diabetes (T1D or T2D), and/or cardiovascular disease 
  • Preferred experience:
  • Knowledge of chronic kidney disease
  • Experience working with 2D/3D models & organoids
  • Knowledge in computational biology & sequencing
  • Experience working in drug development research setting


We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.


At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.


Novo Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations.


If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at 1-855-411-5290. This contact is for accommodation requests only and cannot be used to inquire about the status of applications.


Novo Nordisk is a leading global healthcare company, founded in 1923 and headquartered in Denmark. Our purpose is to drive change to defeat diabetes and other serious chronic diseases such as obesity and rare blood and endocrine disorders. We do so by pioneering scientific breakthroughs, expanding access to our medicines, and working to prevent and ultimately cure disease. Novo Nordisk employs about 54,400 people in 80 countries and markets its products in around 170 countries. For more information visit

Our US Research & Development hub, located in the Greater Boston area, brings together the best talent to drive life science innovation. Located in Lexington, Watertown and Cambridge, our teams reflect the full scope of R&D, from early research through late-stage clinical development. We are building for the future by creating a distinct R&D community based on collaboration, partnerships, and cutting-edge research across multiple modalities and therapeutic areas. We recognize that improving human health starts here and that patients rely on us. By combining the speed and agility of biotech with the quality, resources, and stability of a large pharmaceutical company, our US R&D hub will benefit from the best of both worlds to develop new medicines that meet the needs of patients.


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75 Hayden Avenue
United States

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