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Associate Scientific Director, GI Inflammation Biomarker Discovery Research

Employer
Takeda
Location
San Diego, CA
Start date
Nov 28, 2023

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Job Details

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Job Description

About the role:

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.

Join Takeda as an Associate Scientific Director where you will lead a small team of scientists to design preclinical target engagement and pharmacodynamic assays and analysis of biomarkers in various animal/in vitro models. You will also lead the development and implementation of a defined strategy for preclinical biomarker development that will provide data to support goals/strategy of the early clinical development team. As part of the Inflammatory Disease Research team you will report to the Senior Director and Head Celiac Discovery and have a deep knowledge of inflammatory diseases (e.g. IBD), fibrosis and preclinical biomarker development/utility in various disease indications.

How you will contribute:
  • Leads the development of preclinical biomarker strategy, working closely with preclinical pharmacology, DMPK and clinical translational groups to develop integrated translational plans.

  • Lead teams in efficient and effective design/validation of well-defined and controlled methods to measure pharmacodynamic (PD), target engagement (TE) and disease specific biomarkers in preclinical models.

  • Experience in assay technologies including (but not limited to): MSD, ELISA, qPCR, flow cytometry and other technologies used for biomarker development.

  • Expected to develop (and help direct reports develop) and meet goals/timelines/budgets for project teams.

Minimum Requirements/Qualifications:
  • BS with 15+ years research experience, or MS with 13+ years research or PhD with 7+ years of experience. Experience in a scientific discipline of cellular & molecular biology, immunology, or equivalent.

  • Outstanding expertise in autoimmune disease/IBD and biomarker development.

  • Communicates and collaborates with colleagues and management effectively.

  • Up-to-date knowledge of in current scientific advancements in new biomarker technologies and competitive landscape of given indications.

  • Guide the design, optimization, and execution of well-controlled protocols to support biomarkers in preclinical projects with the ability to troubleshoot as needed.

  • Extensive experience in the analysis and interpretation of data from ligand binding assays, flow cytometry and molecular techniques.

  • Previous experience in biomarker assay development and validation is required.

  • Deep understanding of preclinical models of autoimmune disease and/or IBD pathogenesis.

What Takeda can offer you:
  • Comprehensive Healthcare: Medical, Dental, and Vision

  • Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan

  • Health & Wellness programs including onsite flu shots and health screenings

  • Generous time off for vacation and the option to purchase additional vacation days

  • Community Outreach Programs and company match of charitable contributions

  • Family Planning Support

  • Flexible Ways of Working

  • Tuition reimbursement

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Base Salary Range: $137,200 to $196,000, based on candidate professional experience level. Employees may also be eligible for Short-term and Long-Term Incentive benefits as well. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program and Paid Volunteer Time Off. The final salary offered for this position may take into account a number of factors including, but not limited to, location, skills, education, and experience.

In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.

#LI-SB1

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

San Diego, CA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Company

Takeda is a global, values-based, R&D-driven biopharmaceutical leader headquartered in Japan, committed to discover and deliver life-transforming treatments, guided by our commitment to patients, our people and the planet. Takeda focuses its R&D efforts on four therapeutic areas: Oncology, Rare Genetics and Hematology, Neuroscience, and Gastroenterology (GI). We also make targeted R&D investments in Plasma-Derived Therapies and Vaccines. We are focusing on developing highly innovative medicines that contribute to making a difference in people’s lives by advancing the frontier of new treatment options and leveraging our enhanced collaborative R&D engine and capabilities to create a robust, modality-diverse pipeline. Our employees are committed to improving quality of life for patients and to working with our partners in health care in approximately 80 countries and regions.

For more information, visit https://www.takeda.com.

Stock Symbol: TAK

Company info
Website
Location
650 East Kendall Street
Cambridge
MA
02421
United States

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