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Scientist I

Employer
Novo Nordisk
Location
Lexington, MA
Start date
Nov 22, 2023

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Discipline
Science/R&D, Biology, Biotechnology
Required Education
Doctorate/PHD/MD
Position Type
Full time
Hotbed
Genetown, Best Places to Work

Job Details

About the Department

Our Boston Research & Development hub, anchored in the greater Boston area, brings together the best minds in life science innovation. The teams located in facilities in Lexington, Watertown and Cambridge reflect the full R&D continuum, from early research through late-stage clinical development. Here, we are building for the future, creating a distinct R&D community based on collaboration, partnerships, and cutting-edge research across multiple modalities and therapeutic areas. We recognize that improving human health starts here and that patients rely on us. Our greater Boston R&D hub merges biotech speed and agility with large pharmaceutical company quality, resources,and stability, uniting the best of both worlds to develop new medicines for patients.

 

The Position

We are seeking an individual to fill the Scientist I role as it is a key member of Oligonucleotide In-Vivo Pharmacology teams. The candidate will engage in multiple research and discovery efforts that aim to develop therapeutics to treat patients with rare and common diseases. We are seeking a highly skilled scientist with experience in target identification capable of identifying mechanism-of-action and conducting pharmacology studies. This position will involve hands on work  in vivo and in vitro models of disease.  Outcome measures will include a wide range of molecular and cell biology assays. The successful candidate will interact closely with members of the Oligonucleotide In-Vivo Pharmacology team and other groups within Novo Nordisk. You will apply your expertise in animal models and deep understanding of molecular and cellular biology to study hepatic and extrahepatic diseases, play a key role in all phases of drug discovery and clinical development at Novo Nordisk.

 

Relationships

Reports to Senior Director, Oligonucleotide In-Vivo Pharmacology.

 

Essential Functions

  • Provide scientific and technical ability to assess new target and therapeutic hypotheses for the Oligonucleotide In-Vivo Pharmacology group.
  • Experience with animal handling/small rodent surgeries, compound administration in rodents via multiple routes (e.g., intravenous, subcutaneous, intramuscular, intracerebroventricular)
  • Broad expertise in laboratory techniques (e.g., RNA isolation/qPCR, Western blot, ELISA, immunohistochemistry, fluorescence/confocal microscopy, in situ hybridization)
  • Excellent skills in communication, presentation, collaboration, time-management, lab record keeping
  • Work closely with Novo Nordisk research team members to develop molecular and cellular assays to quickly and effectively address key questions related to the safety and efficacy of our drugs
  • Review literature and provide insights to research directions, while making hands-on contributions to the research
  • Develop in vivo model systems and technologies to evaluate efficacy, pharmacodynamics, and mechanisms of action of drug candidates
  • Serve as a role model for compliant behavior that is consistent with the mission, vision and values of the Novo Nordisk organization
  •  

    Physical Requirements

    0-10% overnight travel required.

     

    Qualifications

  • PhD in molecular biology, genetics, or related discipline with 0-2 or more years post-PhD experience in an academic or biopharma/biotech setting with hands-on molecular biology experience
  • Experience in designing and performing molecular and cellular biology techniques, including but not limited to administration of test compounds, collecting tissue samples RNA preparation, RT-qPCR, ELISA, immunohistochemistry, western blot
  • In depth knowledge of, and hands-on experience with, in vitro and in vivo models used for mechanistic investigation and new target identification
  • A true team player with high degree of energy and a passion for contributing to the discovery and development of novel therapeutics
  • Excellent verbal and written communication skills
  • A documented and strong ability to collaborate with colleagues productively in a fast-paced environment
  •  

    We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.

     

    At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.

     

    Novo Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations.

     

    If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at 1-855-411-5290. This contact is for accommodation requests only and cannot be used to inquire about the status of applications.

    Company

    Novo Nordisk is a leading global healthcare company, founded in 1923 and headquartered in Denmark. Our purpose is to drive change to defeat diabetes and other serious chronic diseases such as obesity and rare blood and endocrine disorders. We do so by pioneering scientific breakthroughs, expanding access to our medicines, and working to prevent and ultimately cure disease. Novo Nordisk employs about 54,400 people in 80 countries and markets its products in around 170 countries. For more information visit novonordisk.com.

    Our US Research & Development hub, located in the Greater Boston area, brings together the best talent to drive life science innovation. Located in Lexington, Watertown and Cambridge, our teams reflect the full scope of R&D, from early research through late-stage clinical development. We are building for the future by creating a distinct R&D community based on collaboration, partnerships, and cutting-edge research across multiple modalities and therapeutic areas. We recognize that improving human health starts here and that patients rely on us. By combining the speed and agility of biotech with the quality, resources, and stability of a large pharmaceutical company, our US R&D hub will benefit from the best of both worlds to develop new medicines that meet the needs of patients.

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    Company info
    Website
    Telephone
    617-612-6200
    Location
    75 Hayden Avenue
    Lexington
    MA
    02421
    United States

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