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Scientist II, Bioanalysis

Employer
AbbVie
Location
Irvine, California
Start date
Nov 18, 2023

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Discipline
Science/R&D, Biotechnology
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Beach, Best Places to Work

Job Details

Overview:

The Bioanalytical Scientist II, as part of Local Delivery Translational Sciences (LDTS) at the Irvine, California site at AbbVie is responsible for developing and performing quantitative liquid-chromatography-tandem mass spectrometry (LC-MS/MS) assays to characterize local biodistribution, quantification, and characterization of toxin proteins in biological fluids and tissues. This individual also significantly contributes to developing and performing assays for quantitation of small molecules and metabolites using LC-MS/MS. The Bioanalytical Scientist II serves as a subject matter expert collaborating with colleagues in Clinical Pharmacokinetics, Pre-Clinical Safety, and other researchers to determine how mass spectrometry-based techniques may be useful for addressing key project questions, especially for botulinum toxin, eye care and aesthetics therapeutic areas. 

As a member of a small team, this individual will independently develop, perform, or oversee quantitative non-regulated small and large molecule bioanalysis studies for in vitro and in vivo studies, document experiments, prepare formal reports, and present results to project teams. This individual should be a self-starter who is eager to learn and thrives in a collaborative, fast paced environment, with a desire to make an impact by interacting closely with scientists from other disciplines and functional areas.

Specific Responsibilities include:

  • Develop and implement toxin-related and small molecule bioanalytical LC-MS/MS assays to meet specific research study needs.
  • Mange non-regulated (non-GLP) bioanalytical sample analysis, monitor bioanalysis at external providers and/or coordinate with colleagues at other Abbvie sites to complete sample analysis in a timely manner.
  • Perform experiments in a select agent laboratory.
  • Trains other lab personnel to perform LC-MS/MS assays as needed.
  • Writes formal study reports for submission to regulatory agencies as needed.
  • Maintains state of the art lab equipment such as Sciex triple quadropole instruments.

Education and Experience:

  • BS or equivalent education with typically 7 or more years of experience or MS or equivalent education with typically 5 or more years of experience.
  • Knowledge and experience developing LC-MS/MS assays for small molecule drugs, peptides, and proteins in biological fluids and tissues.
  • Ability to work with minimal supervision.
  • Experience with large molecule quantitation using LC-MS/MS, including biologic drug candidates and potential biomarkers.
  • Strong verbal and written communication skills.
  • Demonstrated record of successful collaborations with scientists, including those from different disciplines and areas of expertise.

Preferred Experience:

  • Sciex LC-MS/MS systems and software.
  • Waters Q-ToF mass spectrometer.
  • Experience with handling proteins and other biological samples.
  • Basic understanding of pharmacokinetics and drug metabolism is helpful.
  • Experience monitoring bioanalytical studies with CROs.
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

This job is eligible to participate in our short-term incentive programs. 

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. 

AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community, and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.


Company

AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, and YouTube.

Stock Symbol: ABBV

Stock Exchange: NYSE

Company info
Website
Telephone
1-800-255-5162
Location
1 North Waukegan Road
North Chicago
Illinois
60064
US

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