We are seeking a highly motivated and experienced In Vitro biologist/Molecular Pharmacologist to join our drug discovery team. This role will be at the Senior Scientist or Principal Scientist level depending on experience. The successful candidate will have a proven track record driving drug discovery programs with in vitro biology support from target assessment through lead optimization. We are looking for a passionate scientist who can successfully work in multi-disciplinary teams across common target classes to advance target validation and early drug discovery efforts.
Our drug discovery and early clinical development team includes a cross-functional group of scientists and drug developers with experience working on all common target classes and therapeutic areas. The group is supported by more than 100 software developers and engineers as well as a large-scale compute infrastructure to apply our proprietary physics-based drug design and optimization platform. Several programs we have worked on have achieved Development Candidates, including progression to clinical development and FDA approval. You can view our entire pipeline of wholly-owned programs and collaborations here.
Who will love this job:
A molecular pharmacologist with in depth knowledge of protein biochemistry, enzymology, and biophysics
A self starter who has extensive experience with in vitro biology assay development and execution
What you will do:
Guide research strategy for exploratory and early stage drug discovery efforts
Work as the in vitro biology or molecular pharmacology lead for drug discovery programs and manage experimental design, development and implementation of biochemical, biophysical and cell based assays for novel protein targets
Responsible for data review, analysis and interpretation of in vitro results, and troubleshooting issues related to drug discovery projects.
Independently manage CRO scientists to support, guide and troubleshoot IVB assay development
Support ongoing drug discovery programs with in vitro biology and molecular pharmacology expertise
Take part in new target identification and tractability assessment
What you should have:
PhD in molecular pharmacology, biochemistry, or related field with 3+ years of experience in pharmaceutical or biotechnology industries
In depth knowledge of protein biochemistry, enzymology, and biophysics
Extensive experience in in vitro biology assay development and execution as it relates to HitID, LI, LO phases of drug discovery
Demonstrated success in applying in vitro biology tools to support and advance drug discovery programs
Experience in biophysical techniques such as SPR, MST, ITC, etc. desired
Deep understanding of molecular and cell biology desired
Experience managing external studies at CROs desired
Demonstrated ability to multi-task and collaborate effectively with other scientists and research associates to accomplish goals on tight timelines
Comfortable working across a number of disease areas and able to shift gears quickly
Must be open to change and the unknown with a creative and resourceful nature; a self-starter, proactive and results-oriented with high performance standards
Excellent oral and written communication skills; must be able to accurately document results according to best scientific practice
Skilled at working in a multidisciplinary environment
Pay and perks:
Schrödinger understands it’s people that make a company great. Because of this, we’re prepared to offer a competitive salary, stock options, and a wide range of benefits that include healthcare (with dental and vision), a 401k, pre-tax commuter benefits, a flexible work schedule, and a parental leave program. We have catered meals in the office every day, a company culture that is relaxed but engaged, and over a month of paid vacation time. Our Administrative and Human Resources departments also plan a myriad of fun company-wide events. New York is home to our largest office, but we have teams all over the world. Schrödinger is honored to have been selected as one of Crain's New York Best Places to Work for the past three years running.
Estimated base salary range: $130,000 - $180,000 (NYC only). Actual compensation package is dependent on a number of factors, including, for example, experience, education, degrees held, market data, and business needs. If you have any questions regarding the compensation for this role, do not hesitate to reach out to a member of our Strategic Growth team.
Sound exciting? Apply today and join us!
As an equal opportunity employer, Schrödinger hires outstanding individuals into every position in the company. People who work with us have a high degree of engagement, a commitment to working effectively in teams, and a passion for the company's mission. We place the highest value on creating a safe environment where our employees can grow and contribute, and refuse to discriminate on the basis of race, color, religious belief, sex, age, disability, national origin, alienage or citizenship status, marital status, partnership status, caregiver status, sexual and reproductive health decisions, gender identity or expression, sexual orientation, or any other protected characteristic. To us, "diversity" isn't just a buzzword, but an important element of our core principles and key business practices. We believe that diverse companies innovate better and think more creatively than homogenous ones because they take into account a wide range of viewpoints. For us, greater diversity doesn't mean better headlines or public images - it means increased adaptability and profitability.