This job has expired

You will need to login before you can apply for a job.

Principal Scientist, in vivo - Cancer Immunology

Regeneron Pharmaceuticals, Inc.
Tarrytown, New York
Start date
Nov 7, 2023

View more

Job Details


We are seeking a skilled and driven Ph.D. scientist with a proven background in tumor immunology, autoimmunity, or both to join our Immunology and Inflammation team. Our team contributes to discovery and development of novel therapeutics in the Cancer Immunology group at Regeneron.

In this role, you will be responsible for designing and executing a variety of cell-based immunological assays and in vivo experiments using tumor and autoimmune mouse models. This role will employ industry-leading technologies to address pertinent questions in cancer immunology and autoimmunity.

Please see our relevant published work:

Waite JC et al., Sci. Transl. Med. (2020). DOI: 10.1126/scitranslmed.aba2325

Skokos D et al., Sci. Transl. Med. (2020). DOI: 10.1126/scitranslmed.aaw7888

As a Principal Scientist in the Cancer Immunology team, a typical day might include the following:

  • Developing, optimizing, and performing various immunoassays to evaluate therapeutic candidates' impact on immune cell function and phenotype, including advanced techniques such as multicolor flow cytometry and fluorescence microscopy.

  • Independently planning and executing in vivo studies using tumor and autoimmune mouse models. These will include treatments with injections through various routes (IP, IV, SC), blood and tissue collection for downstream analysis of immune responses.

  • Analyzing data using biological and statistical software such as OMIQ, Prism, Excel, etc.

  • Collaborating with cross-functional scientists to drive target validation and therapeutic antibody development.

  • Delivering impactful presentations to colleagues across our business, including senior leadership.

  • Writing protocols and study reports, maintaining accurate electronic records.

  • Routinely reviewing relevant literature, attending scientific meetings, and improving expertise in the field of Immunology and Immuno-Oncology.

  • Training and management of research associates as needed.

This role might be for you if you:

  • Get excited about developing immunotherapies that promote a tumor-specific and durable immune response to eradicate cancer for patients.

  • Have a passion for innovation and desire to lead new scientific directions.

  • Are a team player with a collaborative spirit.

  • Possess excellent communication, organization, and time management skills.

  • Independently design and execute experiments, analyze data, and interpret results.

  • Are confident with multitasking and managing multiple projects simultaneously.

This role requires a Ph.D. in immunology, immuno-oncology, or a related field, 5+ years of relevant industry and/or academic related experience, and a strong record of innovation and publications. Proven expertise in T cell biology with experience using mouse tumor and autoimmune models, including high dimensional immunophenotyping, is required. Proficiency with fluorescence microscopy and advanced imaging techniques is a plus.

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits including health and wellness programs, fitness centers and equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.

The salary ranges provided are shown in accordance with U.S. law and apply to U.S. based positions, where the hired candidate will be located in the U.S. If you are outside the U.S, please speak with your recruiter about salaries and benefits in your location.

Salary Range (annually)

$121,200.00 - $197,800.00


Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to seven FDA-approved treatments and numerous product candidates in development, all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye disease, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, infectious diseases, pain and rare diseases.
Regeneron is accelerating and improving the traditional drug development process through our proprietary VelociSuite® technologies, such as VelocImmune® which produces optimized fully-human antibodies, and ambitious research initiatives such as the Regeneron Genetics Center, which is conducting one of the largest genetics sequencing efforts in the world.

Stock Symbol: REGN

Stock Exchange: NASDAQ

FacebookTwitterInstagramYouTube Logo

Company info
Corporate Headquarters
777 Old Saw Mill River Road
New York
United States

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert