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Senior Quantitative Systems Pharmacologist I (On-Site, IL Based)

Lake County, Illinois
Start date
Nov 4, 2023

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Job Details


The Senior Quantitative Systems Pharmacologist I develops mathematical models (PBPK models) to answer relevant clinical and biopharmaceutics questions for various project teams. Responsibilities: Executes PBPK on one or more studies to answer specific clinical and biopharmaceutics questions Contributes to PB/PK modeling or mechanistic modeling plans to drive therapeutic area success in areas including PK/PD, toxicodynamics, and biopharmaceutics
Performs model optimization, parameter estimation, and model verification of existing PBPK models
Writes, communicates, and presents PBPK and/or system pharmacology materials; presents modeling and simulation materials in reports and internal/external meetings Contributes to drug development teams by preparing PK/PD interpretations of reports for regulatory filings, clinical protocols, DDI study designs and in support of formulation selection, and dissolution specifications Understands regulatory advances, strengths, weaknesses, opportunities, and threats for model-informed drug development Performs literature review and regulatory document review to ensure state-of-the-art modeling activities Contributes to presentation of model results for external publications, project reviews, reports and/or regulatory submissions Participates in external scientific groups to promote modeling and simulation activities
Qualifications: PharmD with 1+ years of experience or PhD with 0+ years of experience in Pharmacokinetics, Pharmacology, Systems Biology, Bio-Engineering, Mathematical Biology or a related area Demonstrated proficiency on PBPK
Demonstrated experience with modeling and simulation software including MATLAB, R, Simcyp, GastroPlus, or PK-Sim and/or other relevant software Demonstrated ability to accomplish one or more of PBPK modeling, biopharmaceutics, or pharmacometric (PK/PD) activities from planning to implementation through completion Excellent communication skills Key leadership competencies: Builds strong relationships; performs efficiently in joint interdisciplinary teams; learns fast; can change course quickly where indicated; open to suggestions and experimentation for improvement

AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community, and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.


AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on Twitter, Facebook, Instagram, and YouTube.

Stock Symbol: ABBV

Stock Exchange: NYSE

Company info
1 North Waukegan Road
North Chicago

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