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Scientific Director - Synthetic Peptide Chemistry (SMDD)

Eli Lilly and Company
Indianapolis, Indiana
Start date
Nov 3, 2023

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Science/R&D, Chemistry
Required Education
Position Type
Full time
BioMidwest, Best Places to Work

Job Details

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

An opportunity for an outstanding, talented, and highly motivated peptide chemistry scientist is available in the Synthetic Molecule Design and Development (SMDD) division @ Eli Lilly and Company! The successful candidate will join a highly dynamic and cross-functional Department pursuing sustainable synthetic peptide development and commercialization. The candidate will lead a variety of synthetic peptide commercialization projects, interface with external collaborators, and advance sustainable, next-generation approaches to synthetic peptides at the commercialization level.

Our team is looking for an innovative and energetic peptide chemist with prior experience leading teams and with significant industry knowledge. The scientist will collaborate with and lead a growing team comprised of chemists, analysts, and engineers aimed at development of peptide synthetic routes and optimization of commercial peptide processes. Our peptide group recently commercialized Mounjaro, which is one of many exciting synthetic peptides in our portfolio. The candidate is expected to contribute at a strategic level to enable new sustainable approaches to synthetic peptides.

This position will also require the candidate to present their findings and progress to project teams and senior management across Lilly, as well as externally through journal publications and conference presentations. The candidate will work in a highly collaborative environment with key collaborators located across the United States, Asia, and Europe; therefore, a demonstrated record of collaboration and communication skills is expected.

Top candidates for this position will:
  • Demonstrate excellence in multiple modes of peptide synthesis including hybrid peptide chemistry in use for the manufacture of Mounjaro.

  • Have experience leading a team of scientists developing peptide synthesis routes.

  • Enable the design, development, and implementation of sustainable, innovative processes for the synthesis of complex peptides.

  • Adopt green chemistry and engineering as a means of effecting a paradigm shift to reduce the environmental footprint in the synthetic peptide field: Synthetic Peptide Sustainability Challenges.

  • Have familiarity with chromatography, mass spectrometry, optical spectroscopy, and peptide automation.

  • Have strong technical problem-solving ability and have an internal motivation to succeed in team environments.

  • Have a track record of innovative scientific research, as demonstrated by publication in high quality, peer reviewed journals and presentations at external conferences.

Position Responsibilities:
  • Lead a team of outstanding peptide chemists designing sustainable synthetic peptide processes.

  • Provide oversight for development of multi-kg synthetic peptide processes at contract manufacturing organizations for peptide products of similar complexity to Mounjaro.

  • Educate contract manufacturing organizations in best practices for peptide development and manufacture.

  • Engage with Eli Lilly’s Development and Manufacturing organizations to develop a deep understanding of new initiatives and improve existing scientific processes.

  • Present research findings at internal forms as well as external conferences and publish in high quality, peer-reviewed journals. Strong written and verbal communication to speak to both technical and business-related implications of your work.

Basic Qualifications:
  • PhD in Chemistry or related field with minimally 7 + years of pharmaceutical industry experience and experience leading a group of scientists.

Additional Skills/Preferences:
  • Fluent in English

  • Experience within the pharmaceutical sector is strongly preferred.

  • Good interpersonal skills and a sustained tendency for collaboration.

  • Ability to learn and apply technical knowledge to meet changing project needs.

  • Flexibility and ability to prioritize work to meet interpersonal and scientific goals.

  • Demonstrated leadership capabilities especially in a team environment.

  • Ability to balance multiple activities, prioritize and handle ambiguity.

Additional Information:
  • Travel: 0 to 10%

  • Position Location: Indianapolis, IN; Lilly Technology Center-North (LTC-N)

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.



Science has been our calling from the beginning. Colonel Eli Lilly founded the company in 1876 and charged employees to “take what you find here and make it better and better.” More than 147 years later, we remain committed to his vision through every aspect of our business and the people we serve, starting with discovering the best treatments for those who take our medicines and extending to health care professionals, employees and the communities in which we live. Moreover, you can also count on the team at Lilly to be incredibly civic-minded, supporting our communities through philanthropy, volunteerism, and a creative and innovative can-do spirit. 

Company info
893 S Delaware St
United States

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