Associate Scientist, Process Development (API Crystallization and Engineering / Material Science)
United States - California - Foster City
Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead’s therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.Making an impact on a global scale
Inclusion is one of the company’s five core values. That’s because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.
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Job DescriptionAssociate Scientist, Process Development: API Crystallization and Engineering
/ Material Science
Gilead Sciences, Inc. is a research-based biopharmaceutical company founded in 1987. Together we deliver lifesaving therapies to patients in need. With the commitment and drive you bring to the Pharmaceutical Development & Manufacturing (PDM) workplace, you will be part of a team that is changing the world and helping millions of people live healthier, more fulfilling lives. You will see the tangible results of your contributions, where every individual matters, and everyone has a chance to enhance their skills through on-going
development. Our scientific focus has resulted in marketed products that are benefiting hundreds of thousands of people, a pipeline of late-stage drug candidates, and unmatched patient access programs to ensure medications are available to those who could otherwise not afford them. By joining PDM at Gilead, you will further our mission to address unmet medical needs and improve life by advancing the care of patients with life-threatening diseases.Specific Responsibilities:
Work in collaboration with project team members including process chemists, analytical chemist, and formulation scientists to screen, characterize, identify, and select API/intermediate form candidates. Perform salt/cocrystal screens to identify potential new forms of the API. Conduct scientific research to design, develop, and scale up crystallization/isolation processes to deliver selected forms with desired purity, stability profiles and particle characteristics. Knowledge, Experience and Skills:
- Preferred degree in Chemical Engineering, Chemistry or related scientific discipline
- Fundamental understanding of solid-state chemistry, thermodynamics and kinetics of polymorphism and crystallization
- Various isolation process development, modeling, and scale-up including crystallization, filtration, drying, wet/dry milling
- Experience with salt screening to improve chiral resolution of target molecules
- Familiarity with solid form characterization techniques such as XRPD, DSC, TGA, DVS, NMR, SEM, and PSD
- Excellent communication (both verbal and technical) and interpersonal skills
- Works on a wide range of problems where analysis of situations or data requires evaluation of intangible variables, requiring regular use of ingenuity and creativity
- Demonstrates technical proficiency, scientific creativity, collaboration with others and independent thought in suggesting experimental design and research strategy
- Must think critically and creatively and be able to work independently, determine appropriate resources for resolution of problems and have strong organizational and planning skills
Please include a Research Summary with application
- Master's degree and 3 + years of relevant experience; or Bachelor's degree and 5+ years of relevant experience.
The salary range for this position is: $120,445.00 - $155,870.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.
For additional benefits information, visit: https://www.gilead.com/careers/compensation-benefits-and-wellbeing
* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.
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As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact firstname.lastname@example.org
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For Current Gilead Employees and Contractors:
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to apply for this job.