Research Associate I/II, Biochemistry

Research Associate I/II, Biochemistry

As a Research Associate I/II, Biochemistry, you will perform research in collaboration with others on assigned projects and will be a member of the Protein Chemistry Group supporting the discovery and optimization of small molecule and bio-therapeutics. With direction by research scientists, you will provide technical support for developing and implementing core recombinant protein expression, purification, and analytical technological platforms. Further, you will be responsible for executing research experiments, data integrity, and communication of results in a matrix environment.

Good things are happening at Omeros! 

Come join our Discovery Protein Chemistry Team! 

Who is Omeros?   

Omeros is an innovative biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, immunologic diseases (e.g., complement-mediated diseases) and cancers. Omeros’ lead MASP-2 inhibitor narsoplimab targets the lectin pathway of complement and is the subject of a biologics license application pending before FDA for the treatment of hematopoietic stem cell transplant-associated thrombotic microangiopathy. Narsoplimab is also in multiple late-stage clinical development programs focused on other complement-mediated disorders, including IgA nephropathy, atypical hemolytic uremic syndrome and COVID-19. OMS906, Omeros’ inhibitor of MASP-3, the key activator of the alternative pathway of complement, is in a Phase 1 clinical trial. For more information about Omeros and its programs, visit  www.omeros.com.

What are your job responsibilities?

• Performing a variety of routine and non-routine research assignments as supervised by a Ph.D. scientist
   
• Conducting routine molecular biology bench work (e.g. primer design and site-directed mutagenesis, plasmid DNA purification, sequencing)
   
• Performing routine eukaryotic cell culture work (e.g. cell passaging, viability determination and transient transfection)
   
• Purifying recombinant proteins using standard chromatographic techniques (e.g. affinity chromatography, size-exclusion chromatography)
   
• Characterizing protein purity and quality using standard biochemical techniques (e.g. SDS-PAGE, Western blotting, thermal shift assays)
   
• Maintaining a detailed and up-to-date electronic lab notebook
   
• Analyzing and summarizing data, presenting at internal meetings, and communicating regularly with managers and coworkers on experiment progress 
   
• Managing laboratory equipment and consumables
   

Education, Experience, Skills, and Knowledge Required:

• BS degree preferred with 4 years of related experience or an MS degree with related experience
  
• Familiarity with standard protein biochemical and biophysical techniques is preferred
• Familiarity with standard biochemistry lab equipment (e.g. FPLC instruments, shakers, centrifuges, etc.
• Knowledge of scientific principles and concept
• Knowledge of the principles and practices of computer applications including word processing, spreadsheet, database management, and presentation software, and Internet search engine
• Written and verbal communication and presentation skills
• Must have the ability to build and maintain positive relationships with management, peers, and subordinates  
• Must be able to communicate procedure, experiments and results to peers and management
• Problem-solving skills

Behavioral Competencies Required:  

• Must have the ability to build and maintain positive relationships with management, peers, and subordinates 
• Must be able to communicate procedure, experiments and results to peers and management

Physical Demands Required: 

• Intermittent physical activity including bending, reaching, pushing, pulling, or lifting up to 40 lbs.
• May encounter prolonged periods of sitting
• This position requires working with and near hazardous material
   

Compensation and Benefits:

Omeros is proud to offer a competitive total compensation package designed to support the lives of our employees and their families. The wage scale for this position for an RA I is $66,000 to $82,000 per year and for an RA II, $75,000 to $91,000 per year.  Salaries will be determined based on knowledge, skills, education, and experience relevant to the role.  Employees are offered medical, dental, vision and life insurance and a 401k plan with a company match.  Employees accrue three weeks of vacation and 80 hours of sick time on an annual basis and receive ten paid holidays throughout the calendar year.  This position is eligible for bonus and stock options. To learn more about Omeros, please visit www.omeros.com. 

Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes. 

It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to  hr@omeros.com   or contact Omeros, asking for Human Resources, at (206) 676-5000.