About the role:
At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.
Join Takeda as a Biomarker Scientist II where you will have a good scientific background in liver fibrosis and/or metabolic dis-eases with experience in biomarker identification and development. You will be will be responsible for biomarker discovery and validation efforts for novel targets and drug candidates and independently or collaboratively design and implement extensive biomarker research strategies to support multiple projects in collaboration with internal research teams, external partners and/or CROs. As part of the Liver Disease Research team, you will report to the Associate Scientific Director and work with the Gastroenterology Drug Discovery Unit (GI DDU).
How you will contribute:
Develop and implement new biomarker concepts for the treatment of liver fibrosis and other chronic liver diseases. This includes biomarker identification, development and validation etc.
Develop and oversee novel scientific biomarker projects in collaboration with internal and external partners.
Establishes project direction integrating science, key technical knowledge, and program objectives.
Perform lab bench work on target and drug candidate discovery, validation and mechanism of action studies using contemporary in vitro/ in vivo methods and tools.
Participate on cross-functional teams and provide technical leadership in area of expertise.
Proactively identify complex obstacles to progress in specific areas; recommend and implement solutions using a diverse set of resources; regularly add value to research projects through creative ideas.
Prepare technical reports, summaries and quantitative analyses in written and/or oral form.
Communicate with colleagues effectively.
Present data to other scientific staff or cross-functional project team; may present data/posters to external research or scientific community and publish research results as appropriate.
Act as a biomarker lead to be involved in different stages of portfolio projects to provide input and contribute to Go or NoGo decisions for various milestones.
Performs as a role model supporting Takeda culture and follow policies.
Ph.D. degree in biology, cardio/metabolic diseases, or immunology or molecular pharmacology with relevant post-doc experience with 2+ years of experience, or
MS with 8+ years of experience, or
BS with 10+ years’ experience.
Previous experience in NASH/chronic liver disease or fibrotic diseases or understanding of liver disease pathogenesis and pre-clinical therapeutic mechanisms of action research.
Demonstrated ability to independently design and solve scientific problems using multiple, state-of-the-art technologies, experimental methods, and approaches is required.
Previous experience in relevant protein and RNA-based assays as well as use of multiomic approaches for biomarker discovery, validation or development is preferred.
Previous experience and lab skills to address various types of biomarkers, modalities, and matrices, across animal models and human samples is preferred.
Previous experience with translational biomarker research and working experience with clinical samples is preferred.
Previous experience of using Omics platforms and collaboration with computational biologists.
Good project management experience with a good understanding in various scientific disciplines in drug discovery (toxicology, DMPK, pharmacology etc.) is a plus.
Demonstrated track record by publications in scientific journals.
Good communication skills (oral, written, and presentation) and a good team player.
What Takeda can offer you:
Comprehensive Healthcare: Medical, Dental, and Vision
Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan
Health & Wellness programs including onsite flu shots and health screenings
Generous time off for vacation and the option to purchase additional vacation days
Community Outreach Programs and company match of charitable contributions
Family Planning Support
Flexible Ways of Working
More about us:
At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.
Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
Base Salary Range: $130,200.00 to $186,000.00, based on candidate professional experience level. Employees may also be eligible for Short-term and Long-Term Incentive benefits as well. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program and Paid Volunteer Time Off. The final salary offered for this position may take into account a number of factors including, but not limited to, location, skills, education, and experience.
In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.Locations
San Diego, CAWorker Type