Senior Scientist - Molecular Analytics

HOW MIGHT YOU DEFY IMAGINATION?

Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Senior Scientist - Molecular AnalyticsLive

What you will do

Lets do this. Lets change the world. In this vital role you will be part of the Molecular Analytics group providing scientific and technical expertise to support early discovery research through to later stage molecule optimization and late-stage selection of Amgens pipeline of drug candidates. This position is an exciting opportunity to unlock the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics.

• Execute assays to assess mAbs, MsAb and other biotherapeutic physical, chemical, thermal and colloidal stability and manufacturability using multiple analytical techniques, including, but not limited to, liquid chromatography methods such as aSEC, aCEX, aHIC, , rheology, calorimetry, self-interaction spectroscopy, light scattering and solubility assays
• Perform intact mass analysis, glycan analysis, characterization etc. using LC-MS and LCMS/MS peptide mapping capabilities to support early-stage pipeline. Implement and/ or develop sensitive high-throughput, low material consumption assays for biological attribute prediction
• Generate, process and use large analytical data sets for the application of biomolecule attribute and manufacturability prediction and machine learning purposes
• Manage timelines, therapeutic projects and cross functional teams and departmental collaborations
• Develop collaborations with both internal and external partners. For example, clients in early research protein cloning, expression and purification; process development; university and external research institutes
• Communicate (verbal and in written) scientific concepts and results
• Work independently in advancing projects and studies within required deadlines
• Keep current with field of expertise, participate and advance drug development, technologies and information services programs within Amgen
• Demonstrate external scientific eminence in the form of peer-reviewed publications and conference presentations
• Follow protocols and procedures, maintain accurate records in an electronic lab notebook, and generate quality data for use in drug development and regulatory filings

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a scientist with these qualifications.

Basic Qualifications:

Doctorate degree

Or

Masters degree and 4 years of biopharmaceutical Analytical Chemistry, Biochemistry or equivalent experience

Or

Bachelors degree and 6 years of biopharmaceutical Analytical Chemistry, Biochemistry or equivalent experience

Preferred Qualifications:

• PhD or Post-Doc level qualification with an emphasis in analytical characterization and biological attribute prediction.
• Expertise in biophysical characterization of proteins to assess critical quality attributes
• Deep understanding of protein aggregation, stability and manufacturability would be an advantage
• Knowledge of statistical processing of data, including related software like RStudio and Jupyter Notebooks Excel, Spotfire, JMP or ArrayStudio
• Knowledge of high-level data interpretation, ideally for molecule manufacturability will be advantageous. Knowledge of AI/ML processes is desirable
• Knowledge of multiple chromatographic softwares (ChemStation, Chromeleon), Astra (SECMALS/ QELLS), Tecan scripts (automation), TA and NanoTemper (calorimetry) software would be advantageous
• Relevant experience working as part of a multidisciplinary team in a biopharmaceutical setting would also be an advantage

Thrive

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates professional and personal growth and well-being.

The annual base salary range for this opportunity in the U.S. is $126,204 - $141,541.

In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

• Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans and bi-annual company-wide shutdowns
• Flexible work models, including remote work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

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Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancers, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.