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Senior Scientist, Protein Engineering

Employer
Life Edit Therapeutics
Location
Durham, NC
Start date
Sep 21, 2023

View more

Discipline
Science/R&D, Biotechnology
Required Education
Doctorate/PHD/MD
Position Type
Full time
Hotbed
Bio NC

Job Details

The Role:

We are looking for an experienced scientist with a strong background in protein engineering to help expand our therapeutic capabilities and continue to improve our technology discovery platform. We are seeking curious, enthusiastic, competent, and self-motivated individuals to work in our company. This is an exciting opportunity to help build a successful therapeutics company from an early stage.

Here’s What You’ll Do:

  • Design, implement, and troubleshoot experiments to develop and improve genome editing technology.
  • Implement high throughput engineering, directed evolution, and screening assays to discover variants of gene editing systems with improved characteristics.
  • Work on a multidisciplinary team using knowledge and experience in protein engineering to advance therapeutic programs.
  • Analyze experimental data and present scientific results at team research meetings.
  • Contribute to publications and patent applications.
  • Follow advancements in the field of gene editing and gene therapy published in the literature and presented at conferences.

 

Requirements:

  • PhD in Biochemistry, Biology, Biophysics, Chemistry or a related field, with 5+ years of post-graduate school experience.
  • Demonstrated ability to develop screening or selection assays in cells (bacterial and/or mammalian).
  • Experience with high throughput screening and selection methods such as FACS technology.
  • Research experience with genome editing technologies, nucleases, and/or DNA modified, or DNA binding proteins is strongly preferred.
  • Experience with artificial intelligence and/or machine learning methods for protein engineering is preferred
  • Experience with molecular biology, specifically library generation.
  • Scientific background in biochemistry, strong understanding of protein structure and function.
  • Demonstrated ability to develop assays to demonstrate protein (preferably enzyme) activity.
  • Relevant technical skills for data analysis, DNA and protein sequence analysis, ELN documentation, and presenting results.
  • Demonstrated ability to collaborate in a team-oriented environment.
  • Exceptional oral and written communication skills.
  • Preferred experience with and conceptual understanding of NGS techniques.

Why join Life Edit and the ElevateBio ecosystem?

Life Edit Therapeutics is an integrated subsidiary of ElevateBio, a technology-driven cell and gene therapy company that is accelerating access to the cutting-edge technologies and expertise that can change the future of medicine. Our integrated model combines multiple R&D technology platforms – including Life Edit gene editing – and cGMP manufacturing to power the discovery and development of advanced therapeutics.Our ecosystem is designed to enhance speed, delivery, and probability of success to change patient lives.

Life Edit is an integral part of ElevateBio’s ecosystem of platform technologies and is pioneering focused next-generation gene editing technologies and therapeutics. Located in Durham, NC, members of Life Edit work closely with the ElevateBio Research and Development and BaseCamp manufacturing teams in Waltham, MA. Life Edit is advancing therapeutic programs in collaboration with industry partners while building its own internal pipeline of gene editing therapies. We are looking for a unique individual who can continue to lead the cultural development of Life Edit and build on its momentum as an integral part of the ElevateBio ecosystem.

Our Mission:
To power the creation of life-transforming cell and gene therapies, at a speed the world deserves.

Our Vision:
We seek to be the world’s most indispensable cell and gene therapy technology company, redefining how companies operate, how products are created and how disease is treated.

ElevateBio is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. ElevateBio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Company

Life Edit Therapeutics, an ElevateBio company, is a next-generation genome editing company that has built a highly innovative platform with one of the world’s largest and most diverse collections of novel RNA-guided nucleases (RGNs) and base editors. The platform allows Life Edit to target any genomic sequence and develop novel human therapeutics for the most challenging genetic diseases by enabling ex vivo engineering for cell therapies and regenerative medicines and in vivo delivery of gene therapies. In addition to developing its own pipeline of cell and gene therapies, Life Edit Therapeutics will continue to strengthen its platform of genome-editing enzymes, provide gene-editing expertise to strategic partners, and form other third-party partnerships to discover and develop new therapies.

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Company info
Website
Location
507 Airport Blvd. Suite 101
Morrisville
NC
27560
US

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