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Sr. Engineer II, Process Development

Moderna, Inc.
Norwood, MA
Start date
Sep 6, 2023

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Job Details

The Role:

The Pilot Scale Operations team is seeking a highly skilled and motivated full-time Sr. Engineer II to support nucleic acid pilot-scale production. Qualified candidates will have chromatography, enzymatic reaction, and tangential flow filtration expertise, and experience with experience with scaling and technology transfer of these unit operations. A successful candidate should have experience in large and small-scale equipment maintenance and troubleshooting; as well as authoring and updating equipment specific SOPs. This position will require excellent communication and organizational skills, as well as a focus on operational excellence and process optimization. Candidates are expected to lead people and projects, often cross-functionally. A successful candidate must demonstrate the independent drive and collaborative spirit to operate in a dynamic, fast-paced environment.

Heres What Youll Do:

  • Be the receiving unit for technology transfer from Modernas Process Development teams, focusing on Nucleic Acid sciences, including DNA and mRNA

  • Be expected to matrix lead other development scientists / engineers in defining process development and scale-up strategy, and implementing process control strategies

  • Operate, maintain, and trouble shoot reaction, tangential flow filtration and chromatography skids (AKTA and Axichrom)

  • Lead experiments to confirm robust process performance

  • Characterize Nucleic Acid properties through collaboration with analytical and technical teams.

  • Demonstrate and implement GLP-enabling best practices

  • Demonstrate process suitability and manufacturability through scale-up chromatography, enzymatic reaction, tangential flow filtration, and other technologies

  • Update and write standard operating procedure (SOPs) associated with Nucleic Acid production as needed

  • Assist Pilot Development Lab and technical teams with project goals, resourcing, and scheduling

  • Practice safe work habits and adhere to Moderna safety procedures and guidelines

  • Adhere to documented waste handling procedures to respect environmental regulations

Heres What Youll Bring to the Table:

  • Degree in Chemical/Biomedical Engineering, Pharmaceutical Sciences, Biochemistry, Biology, or related technical discipline

  • Minimum of 3 years (PhD) or 10 years (BS) relevant industry experience

  • Demonstrated success in bioprocess development and scale-up, technical problem solving, and tech transfer are essential

  • Experience with synthesizing mRNA and/or DNA

  • Hands-on experience with chromatography, tangential flow filtration, normal flow filtration, and enzymatic reactions

  • Strong communication skills as you will be responsible for having multiple interactions across operating and development teams

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

  • Highly competitive and inclusive medical, dental and vision coverage options
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
  • Family care benefits, including subsidized back-up care options and on-demand tutoring
  • Free premium access to fitness, nutrition, and mindfulness classes
  • Exclusive preferred pricing on Peloton fitness equipment
  • Adoption and family-planning benefits
  • Dedicated care coordination support for our LGBTQ+ community
  • Generous paid time off, including:
    Vacation, sick time and holidays
    Volunteer time to participate within your community
    Discretionary year-end shutdown
    Paid sabbatical after 5 years; every 3 years thereafter
  • Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
  • 401k match and Financial Planning tools
  • Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
  • Complimentary concierge service including home services research, travel booking, and entertainment requests
  • Free parking or subsidized commuter passes
  • Location-specific perks and extras!

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, theinfrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our peopleare the driving force behind our scientific progress and our culture.Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit to learn more about our current opportunities.

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. Were focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the Talent Acquisition Partner or contact the Accommodations team at (EEO/AAP Employer)



Moderna is advancing messenger RNA (mRNA) science to create a new class of transformative medicines for patients. Moderna’s platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, providing the Company the capability to pursue in parallel a robust pipeline of new development candidates. Moderna is developing therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases and cardiovascular diseases, independently and with strategic collaborators.

mRNA is now a turning point in the history of science, medicine, technology, even humankind itself. With this breakthrough discovery, many of the world’s biggest and most challenging medical problems are no longer a question of “how?” but merely a question of “when?”

Come with us as we pursue the uncharted reaches of possibility and make your mark on the future of medicine.


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Company info
200 Technology Square
Cambridge, MA
United States

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