Scientist, Neurological Disease Gene therapies

The Enzyme Replacement Therapy group, part of Regeneron Genetics Medicine, is seeking an independent and motivated Scientist/Sr. Scientist to support the development of cutting-edge gene therapies for treating lysosomal diseases and other neurological disorders.

The ideal candidate will have strong in vivo and molecular biology skills to contribute to new therapies using our technology platforms, including blood-brain barrier crossing, gene therapy, CRISPR-mediated gene editing, VelociGene mouse models, and VelocImmune antibody platforms. We hope you are excited by the opportunity to lead innovative projects and further expand our CNS delivery portfolio.

As a Scientist/Sr. Scientist, a typical day might include the following:

• Designing, performing, analyzing, and troubleshooting in vitro and in vivo experiments to validate BBB-crossing enzyme replacement therapies

• Performing basic molecular biology techniques (Western blotting, ELISA, enzymatic activity assays, immunofluorescence staining, plasmid cloning)

• Conducting in vivo gene therapy studies in mice, including dosing, behavior testing, harvesting, and analyzing tissues

• Collaborating with other team members and providing support to their programs

• Participating in team meetings and preparing presentations for departmental meetings

This role might be for you if:

• You enjoy working in an innovation-driven, highly collaborative environment

• You have a passion for developing gene therapies for neurological disorders

• You have strong organizational, time-management, and communication skills

• You can effectively balance multiple projects independently

To be considered for this role you typically have a Ph.D. with 0-4 years or a BS/MS with a minimum of 4-6 years of proven experience and expertise in cell biology, molecular biology, neuroscience, lysosomal diseases, or related fields. Extensive experience performing Western blot, ELISA, immunofluorescence staining, and mouse treatment studies is required. Experience with AAV gene therapies and antibody therapies is desired. The level will be commensurate with experience. #RGM

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits including health and wellness programs, fitness centers and equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.

The salary ranges provided are shown in accordance with U.S. law and apply to U.S. based positions, where the hired candidate will be located in the U.S. If you are outside the U.S, please speak with your recruiter about salaries and benefits in your location.

Salary Range (annually)

$103,600.00 - $169,000.00