Research Associate / Senior Research Associate, Biochemical Assays

IDEAYA Biosciences (NASDAQ: IDYA) is a public, clinical-stage synthetic lethality-focused precision medicine oncology company committed to the discovery and development of targeted therapeutics for patient populations selected using DNA sequencing and other molecular diagnostics. Our approach integrates extensive capabilities in identifying and validating translational biomarkers with small molecule drug discovery to select patient populations most likely to benefit from the therapies we are developing. We are applying these capabilities across multiple classes of precision medicine, including direct targeting of oncogenic pathways and synthetic lethality – which represents an emerging class of precision medicine targets. We believe this diversified approach will enable us to deliver the right medicine to the right patient to drive a more robust clinical response.
 
IDEAYA has an industry leading platform and pipeline in Synthetic Lethality. IDEAYA has established strategic collaborations with Amgen and Pfizer supporting its pipeline programs, and also has wholly-owned or controlled clinical and preclinical programs.
 
When you're at IDEAYA, you will be in the midst of brilliant minds working on precision medicine therapies to help cancer patients. We are passionate and committed about being on the forefront of oncology medicine, which means we all have a high internal drive that is at the very core of every person at IDEAYA. We are inquisitive, ask deep questions, and are data-driven innovators who like to collaborate and use team work to move science forward. For more information, please see www.ideayabio.com.

Position Summary:
We are looking for a Research Associate or Senior Research Associate for our Bioassay Screening group. This individual will join a team responsible for developing and performing robust, reproducible biochemical assays to support our small molecule drug discovery pipeline. This position requires a basic knowledge of molecular biology and protein biochemistry techniques, as well as familiarity with biochemical assays, lab automation, and screening approaches. The successful candidate will join an established and highly collaborative Lead Discovery group that includes teams within Cellular assays, Biophysics, Structural Biology, and Protein Sciences.

What you'll do:

• Perform weekly discovery screening cascades and prepare associated data reports.
• Perform automation assisted high-throughput assays as well as follow up studies.
• Develop and implement biochemical assays using diverse approaches (e.g. TR-FRET, Alpha-Screen, fluorescence polarization and more).
• Assist scientists on the team in performing detailed mechanistic studies.
• Contribute to several projects in parallel, balancing duties across project teams.
• Perform all duties in keeping with the IDEAYA’s core values, policies, and all applicable regulations.

Requirements:

• BS/MS with 2+ years of academic or industry research experience in biochemistry or a related scientific discipline.
• Hands-on experience performing biochemical assays is required
• The ideal candidate has a background in small molecule drug discovery and development or relevant academic research experience
• Strong troubleshooting, organization, and planning skills.
• Excellent oral and written communication skills.
• One or more of the following skills is strongly desired but not essential: experience with lab automation using commercial instrumentation, familiarity with kinetics and thermodynamics for biochemistry, and experience with a programming language (e.g. Python, R, Java, Matlab) for scientific data analysis.

Preferred Requirements:

• Ability to thrive in a dynamic environment.
• A desire to learn new skills, concepts, and approaches from experienced scientists.
• Critical thinker with an ability to collaborate effectively across teams and functional areas.
• Capacity to synthesize and integrate complex ideas and to clearly communicate key insights around our targets, mechanisms, and models.
• Skilled at identifying and solving problems, planning, and risk mitigation.
• Curiosity, passion, and a desire to make a difference.

The Company complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law. This position requires you to work onsite at the Company’s facilities, with partial work-from-home flexibility,  and the Company requires that all employees working in its facilities be fully vaccinated (except as required by applicable law). Therefore, this position requires you to be fully vaccinated from COVID-19, subject to reasonable accommodations for medical or religious reasons, and/or as otherwise required by applicable law. The Company considers you fully vaccinated once 14 days have passed since you received either the second dose in a two-dose COVID-19 vaccine series or a single-dose COVID-19 vaccine. The vaccine must have been FDA approved, have emergency use authorization from the FDA, or, for persons fully vaccinated outside of the U.S., be listed for emergency use by the World Health Organization.

Benefits
Along with our highly collaborative and inclusive environment, IDEAYA offers a comprehensive and competitive benefits package that includes (but is not limited to) medical/dental/vision coverage (100% company paid for employees and 90% company paid for dependents), retirement benefits, ESPP and wellness programs. All full-time employees will also be eligible for an annual bonus and equity refresh.

IDEAYA is an equal opportunity employer. In accordance with applicable law, IDEAYA does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets.

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