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Principal Scientist, Ophthalmology

Regeneron Pharmaceuticals, Inc.
Tarrytown, New York
Start date
May 28, 2023

View more

Science/R&D, Biotechnology
Required Education
Bachelors Degree
Position Type
Full time
Pharm Country, Best Places to Work

Job Details

We are seeking a highly motivated Principal Scientist to join our Ophthalmology group, a part of Regeneron Genetic Medicines, with a focus on next-generation novel turn-key therapeutic approaches for restoring and editing genes. You will be specifically responsible for designing and executing preclinical in-vivo experiments as well as in-vitro assays to support Regeneron gene therapy for ophthalmic disorders. 

As a Principal Scientist, a typical day might include the following: 

  • Independently designing projects and planing experiments, taking the lead and advising on in-vivo and in-vitro experimental execution.

  • Analyzing data using biological and statistical software.

  • Utilizing scientific knowledge and expertise in helping with trouble-shooting experiments within team and across departments.

  • Presenting research results to and participate in scientific discussion with multi-disciplinary teams across the company.

  • Following current relevant literature and attending scientific conferences to seek out, recognize, and assess new technologies to maintain expertise in the field ophthalmology research.

  • Generating experimental reports and write manuscripts for journal submission.

This role may be for you if you:

  • Have a passion and knowledge in ocular angiogenesis, ocular gene therapy, and ocular delivery technologies. 

  • Have strong scientific leadership and management ability.

  • Able to align personal goals with company strategy and vision.

  • Have an interest and/or experience mentoring junior scientists.

To be considered for this role, you must have at least a BS/MS degree and 11+ years of relevant experience or a Ph.D. and 3+ years of relevant experience in Pharmaceutical Science, Biotechnology, Biomedical Engineering, Biology, or related field. Industry experience is preferred. We need someone with a strong background in ocular gene therapy or ocular angiogenesis. Must have experience in rodent and rabbit animal handling and procedures, including ocular injections (IVT, sub-retinal, SCS, etc.), in vivo animal eye imaging (SD-OCT), and retinal functional assessment (ERG). Experience in rabbit eye handling (injection, imaging, dissection) is a plus. Experience in tissue collection, ocular tissue dissection, histological techniques, and microscopy/ image analysis is required.

Must have experience with statistical concepts and practical data analysis skills (MacVector, Excel, Prism, Photoshop).

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits including health and wellness programs, fitness centers and equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.

The salary ranges provided are shown in accordance with U.S. law and apply to U.S. based positions, where the hired candidate will be located in the U.S. If you are outside the U.S, please speak with your recruiter about salaries and benefits in your location.

Salary Range (annually)

$121,200.00 - $197,800.00


Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to seven FDA-approved treatments and numerous product candidates in development, all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye disease, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, infectious diseases, pain and rare diseases.
Regeneron is accelerating and improving the traditional drug development process through our proprietary VelociSuite® technologies, such as VelocImmune® which produces optimized fully-human antibodies, and ambitious research initiatives such as the Regeneron Genetics Center, which is conducting one of the largest genetics sequencing efforts in the world.

Stock Symbol: REGN

Stock Exchange: NASDAQ

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777 Old Saw Mill River Road
New York
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