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Research Associate I- Ramani Lab

Gladstone Institutes
San Francisco, CA
Start date
May 25, 2023

View more

Regulatory, Science/R&D, Research, Laboratory
Required Education
Associate Degree
Position Type
Full time
Biotech Bay

Job Details

Lab/Area:Ramani Lab


The Ramani Lab is looking to hire a research associate to assist with wet-lab research in the lab. The Ramani Lab develops and applies novel sequencing technologies to study transcriptional regulation at genome-scale. These include methods to measure chromosome structure, chromosome accessibility, and transcriptional programs in diverse cell types and under different extracellular conditions. The research associate will specifically be involved in generating single-cell and single-molecule sequencing libraries for the Illumina and PacBio sequencing platforms, performing various molecular biological experiments within the lab, and analyzing and reporting on sequencing data results. Candidates should have previous computational experience, some prior molecular biology experience, strong organizational & communication skills, and be capable of working independently.

Job Responsibilities:

The Research Associate will be responsible for carrying out diverse experiments to support the Ramani Lab’s goal of using high-throughput sequencing to understand how mammalian genomes are regulated under different conditions. As such, the research associate will be responsible for carrying out basic and complex molecular biological experiments to create sequencing libraries compatible with various high-throughput sequencing machines. Applicants will be expected to follow and often generate detailed molecular biological protocols to barcode, amplify, and otherwise process both DNA and RNA samples from mammalian cells. Applicants will also be expected to perform quality-control experiments to validate these samples, and sequence these samples on appropriate sequencing instruments. The applicant will also be expected to help analyze and graph the data generated using extant or novel computational pipelines. The Research Associate will also be expected to assist with ordering reagents, aiding with lab organization, and other administrative tasks as needed.


  • Associates degree and 2+ years of relevant experience or B.S./B.A. degree in a relevant field at the time of hire, and some previous molecular biology laboratory experience.

  • Scripting/bioinformatics experience (i.e. Python, R, C++, UNIX)

  • A degree may be in process at the time of application submission, however, the degree must be processed by the appointment effective date.

Preferred Qualifications:

  • Experience with mammalian tissue culture.

  • Laboratory experience generating sequencing libraries for the Illumina and / or Pacific Biosciences platforms.

  • Experience with single-cell/low-input sequencing technologies.

  • Experience in performing or analyzing flow cytometry experiments

  • Experience handling mice and/or mouse tissues

Hiring Range:

$25/hr-$29/hr (DOE)

Additional Information:
  • Title and salary will be commensurate with education and experience.
  • Gladstone is an equal opportunity employer.


Gladstone is an independent, nonprofit life science research organization located in the epicenter of biomedical and technological innovation in the San Francisco Bay Area. Gladstone has created a research model that disrupts how science is done, funds big ideas, and attracts the brightest minds. Gladstone Institutes leads the way for innovative research in the biomedical field. We always seek dedicated and talented individuals to join our team.

Scientists know that using a diversity of approaches is often the most efficient strategy for solving a problem. New and different perspectives engender the very innovation that Gladstone prizes. This is one of the many reasons why we value diversity at Gladstone—be that a diversity of race, culture, religion, mental or physical ability, heritage, age, gender, sexual orientation or other characteristics. Our employees hail from more than 30 countries around the globe and we seek to hire the best and brightest for our diverse team of scientists and administrators. Career opportunities are available in both our administrative offices and our research areas.

Our Benefits
Gladstone offers eligible employees—and their dependents—a comprehensive range of benefits, including health insurance, retirement savings, and professional development.


  • Health and Retirement
    • A choice of medical plans, flexible spending account, and retirement account options that include employer contributions help you take care of your health and your future.
  • Time Away from Work
    • More than just vacation days, our paid and unpaid leave policies offer flexibility to help you confront different stages of life including maternity and paternity leave, as well as other types of family leave.
  • Professional Development
    • Gladstone encourages employees to seek the skills they need to remain at the forefront of their profession. By supporting professional development workshops and continuing education, Gladstone provides employees with the resources they need to evolve in their role and in their career.
  • Gladstone Cares
    • A specially selected suite of benefits to support you in and out of the workplace. Includes resources for dealing with the many stages of life to specific coverage for family planning, and back-up child or elder care coverage.
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1650 Owens Street
San Francisco
United States

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