Research Associate or Senior Research Associate, NGS
- Employer
- OmniAb
- Location
- Emeryville, CA
- Start date
- May 21, 2023
View more
- Discipline
- Regulatory, Research/Documentation, Science/R&D, Research
- Required Education
- Bachelors Degree
- Position Type
- Full time
- Hotbed
- Biotech Bay
Job Details
The Research Associate or Senior Research Associate, Molecular Biology and NGS will play a crucial role in high-throughput B cell screening and sequencing to identify therapeutic candidates for our partners. This position will contribute to the development of novel sample preparation techniques and execute sequencing of antibodies. The successful candidate will be responsible for planning and carrying out small and large projects utilizing developed techniques, as well as piloting independent projects to test new approaches.
About Us:
OmniAb consists of dynamic and innovative scientists that employ a variety of novel platforms to support our partners in discovering next generation therapeutics. At the core of OmniAb is the ability to engineer animals to generate affinity matured human sequence antibodies for use in conventional and novel therapeutic formats. We leverage our proprietary animals with state-of-the-art technology in antigen design, immunization methods and high-throughput single B cell screening to facilitate discovery of best-in-class antibodies. Within OmniAb are also best-in-class capabilities for the discovery and screening in high value ion channel and transporter targets. We are looking for accomplished team players who are enthusiastic to contribute to the technological frontier of drug discovery, contribute to improving human health, and passionate in their desire to collaborate with partners to develop next generation therapeutics. See OmniAb.com for more details about the exciting science being performed at OmniAb.
Responsibilities:
Contribute to the development of novel antibody sequencing approaches and workflows for both bulk and single cells.
Develop, optimize, and troubleshoot molecular biology techniques, including primer design, RT-PCR, RNA and DNA extraction, cDNA generation, qPCR, NGS library preparation and QC, and DNA gel purification.
Execute high-throughput single cell sequencing projects for partner and internal initiatives with exceptional attention to detail.
Collaborate with cross-functional teams, including biologists, engineers, and project managers.
Maintain accurate sample tracking, documentation and reporting of experimental results, ensuring clear communication and actionable insights.
Support day-to-day operations, service, and troubleshooting.
Support and participate in scientific conferences.
Back-up to support other programs.
Other duties as required.
Requirements:
BS or MS in Molecular Biology, Biochemistry, Genetics, or equivalent.
3+ years of relevant experience.
Proven expertise in molecular biology techniques, including PCR, cloning, and cDNA synthesis, NGS preparation.
Experience with Illumina sequencing platforms and library preparation methods.
Thorough knowledge of experimental design, underlying scientific principles, and the ability to analyze and assess results independently.
Strong analytical and problem-solving skills, with the ability to design and optimize experiments.
Strong interest in learning and mastering new laboratory techniques approaches.
Strong communication, record keeping, and organizational skills, and the ability to work in a team environment.
Benefits:
The company offers competitive benefits including Medical, Dental, Vision, Short/Long Term Disability and Life Insurance, as well as 401(k) Match, Stock Options, Bonus, and Paid Leave Time.
Additional Information:
All new hires are required to go through background and reference checks.
OmniAb is an EEO/AA/Disability/Vets employer.
Must be legally authorized to work in the US without sponsorship.
OmniAb celebrates the diversity of life and welcomes all individuals to apply.
Base Pay Range: $60,000 - $120,000/year
The pay range provided is an estimated base range for this role. Exact compensation may vary based on skills, experience, education, and location. We also offer an excellent benefits program which includes a selection of Medical and Dental plans, and Life, AD&D and Short-Term Disability insurance, Tuition Reimbursement, 401(k) with immediate Company match vesting, Company paid holidays, and more!
OmniAb, Inc. is an Equal Opportunity Employer and does not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class.
Company
OmniAb, Inc.’s discovery platform provides pharmaceutical industry partners access to diverse antibody repertoires and high-throughput screening technologies to enable discovery of next-generation therapeutics. At the heart of the OmniAb platform is the Biological Intelligence™ (BI) of our proprietary transgenic animals, including OmniRat®, OmniChicken® and OmniMouse® that have been genetically modified to generate antibodies with human sequences to facilitate development of human therapeutic candidates. OmniFlic® (transgenic rat) and OmniClic® (transgenic chicken) address industry needs for bispecific antibody applications though a common light chain approach, and OmniTaur™ features unique structural attributes of cow antibodies for complex targets.
We believe the OmniAb animals comprise the most diverse host systems available in the industry and they are optimally leveraged through computational antigen design and immunization methods, paired with high-throughput single B cell phenotypic screening and mining of next-generation sequencing datasets with custom algorithms to identify fully human antibodies with superior performance and developability characteristics.
An established core competency focused on ion channels and transporters further differentiates our technology and creates opportunities in emerging target classes. OmniAb antibodies have been leveraged across modalities, including bispecific antibodies, antibody-drug conjugates and others.
The OmniAb suite of technologies span from BI-powered repertoire generation to cutting edge antibody discovery and optimization offering a highly efficient and customizable end-to-end solution for the growing discovery needs of the global pharmaceutical industry.
- Website
- https://www.omniab.com/
- Location
-
5980 Horton Street
Suite 600
Emeryville
CA
94608
United States
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