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Co-op, Ocular

Entrada Therapeutics
Boston, MA
Start date
May 20, 2023

Job Details

The Organization                         

What's happening at Entrada Therapeutics? Our mission is to transform the treatment of devastating diseases and improve patients' quality of life using intracellular biologics. Leveraging our proprietary Endosomal Escape Vehicle (EEV)™ platform, we are creating and advancing a diverse pipeline of oligonucleotide, enzyme, protein, and enzyme-based programs to efficiently target and engage underlying drivers of diseases.

Our novel approach to drug design and delivery addresses current challenges associated with both large and small molecule therapeutics and represents a fundamental advancement in the field of intracellular biologics.

We're a tight-knit, patient-inspired team of experts and leaders in therapeutics development and are excited to grow and attract colleagues who are ready to join a high energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families.

The Perfect FitYou should be a versatile, self-motivated, and looking forward to rolling up your sleeves, as you’ll be involved in all aspects of ocular programs, supporting efforts for testing EEV, antisense oligonucleotides, small interfering ribonucleic acids and gene editing in vitro and in vivo. You should be ready to support our team of drug discovery scientists as we evaluate all the gene targeting modalities and carry out analytical assays for functional validation both in vitro and in vivo.  The Opportunity

In this role you will have the opportunity to be involved in a lot of different aspects of our discovery biology work for the ocular programs, e.g. processing and analyzing samples from in vitro and in vivo studies will be just one of your areas of work. You’ll be expected to work through techniques like RNA/protein extraction, RT-PCR, RT-qPCR, ELISA, western blot, tissue embedding, sectioning and staining. You’ll also have the opportunity to maintain and culture cell lines or tissues for in vitro or ex vivo studies, developing and executing cell-based or ex-vivo assays for validating biological activity of oligonucleotide therapeutics. Lastly, you’ll have the opportunity to prepare SOPs and other reports and publications.

The Necessities

At Entrada, our passion for science, our devotion to patients and our values drive our behavior:
  • Humanity - We genuinely care about patients and about one another.
  • Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
  • Creativity - We are creative problem solvers.
  • Collaboration - We are more than the sum of our parts.
  • Curiosity - We have a growth mindset and push conventional thought and theory.
To thrive on our team, you will need to come with:
  • Undergraduate student in junior or senior year, or graduate student in biotechnology, molecular and cellular biology, pharmacology, biochemistry or similar field
  • Hands-on biochemistry experience with RT-PCR, qPCR, ELISA, fluorescence microscopy and Western blotting is a plus
  • Ability to collaborate with interdisciplinary team with strong communication skills
  • Desire to work in an innovative and collaborative environment pursuing high reward science

The Perks

As a member of the Co-op Program, you will be eligible to participate in the Company’s transportation benefit and may expense up to $150 monthly for commuting purposes. You will also be able to log Holiday hours to be paid for National Holidays. Our location in the vibrant and growing Seaport District is close to all the best that the city of Boston has to offer.

Entrada Therapeutics is an equal opportunity employer. Qualified candidates will receive consideration for employment without regard to race, color, religion, national origin, gender, sexual orientation, gender identity or expression, age, mental or physical disability, and genetic information, marital status, citizenship status, military status, protected veteran status or any other category protected by law.

Third Party Staffing Agencies

Entrada does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Entrada from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Entrada and do not obligate Entrada to pay fees if we hire from those resumes.


Entrada Therapeutics is a biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines, Endosomal Escape Vehicle (EEV™) therapeutics, to engage intracellular targets that have long been considered inaccessible and undruggable. The Company’s EEV therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues with an improved therapeutic index. Through its proprietary, highly versatile and modular EEV platform, Entrada is building a robust development portfolio of oligonucleotide-, antibody- and enzyme-based programs for the potential treatment of neuromuscular diseases, immunology, oncology and diseases of the central nervous system. The Company’s lead oligonucleotide programs include ENTR-601-44 targeting Duchenne muscular dystrophy (DMD) and ENTR-701 targeting myotonic dystrophy type 1 (DM1).

Stock Symbol: TRDA
Stock Exchange: NASDAQ



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6 Tide Street

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