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Senior/ Principal Research Associate Neuromuscular (CONTRACT)

Entrada Therapeutics
Boston, MA
Start date
May 19, 2023

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Science/R&D, Biotechnology
Required Education
Position Type
Genetown, Best Places to Work

Job Details

The Organization

What's happening at Entrada Therapeutics? Our mission is to transform the treatment of devastating diseases and improve patients' quality of life using intracellular biologics. Leveraging our proprietary Endosomal Escape Vehicle (EEV)™ platform, we are creating and advancing a diverse pipeline of oligonucleotide, enzyme, protein and peptide programs to efficiently target and engage underlying drivers of diseases.

Our novel approach to drug design and delivery addresses current challenges associated with both large and small molecule therapeutics and represents a fundamental advancement in the field of intracellular biologics.

We're a tight-knit team of experts and leaders in both therapeutics development and rare disease and are excited to grow and attract colleagues who are ready to join a high energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families.

The Perfect FitYou should be versatile, self-motivated, and looking forward to rolling up your sleeves, as you will be involved in all aspects of neuromuscular and cardiac biology. Your team player mentality and excellent communication skills will allow you to collaborate effectively as you work alongside your team as well as cross-functionally.The Opportunity

This position will support both, portfolio projects as well as discovery research to identify novel targets. You will work with multidisciplinary teams cross-functionally in a matrix environment and will also lead projects with external academic or private collaborators. You will be part of a cutting-edge research team with expertise in developing mechanistic insight into disease biology in the space of neuro/muscular/ cardiovascular indications. You will supervise lab-base scientists. Level will be determined based on experience.

  • Formulate and lead preclinical strategies to identify and validate therapeutic targets in neuromuscular and cardiac disease areas for early discovery programs.
  • Collaborate cross-functionally with diverse group of scientists internally as well as externally.
  • Conceptualize, design and run experiments independently.
  • Present experimental results, both internally and externally.
  • Lead and mentor junior personnel.
  • Be familiar with research advances in neuromuscular and cardiac biology to enhance the portfolio of programs.
  • Be scientifically curious and self-driven with good time management skills.
The Necessities

At Entrada, our passion for science, our devotion to patients and our values drive our behavior:

  • Humanity - We genuinely care about patients and about one another.
  • Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
  • Creativity - We are creative problem solvers.
  • Collaboration - We are more than the sum of our parts.
  • Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

  • BS or MS  in cell biology or related discipline with 5+ years of industry experience. 
  • Hands-on experience with cell and molecular biology techniques including mammalian cell culture, cell-based assays, immunofluorescence, qPCR, and tissue processing is essential.
  • Experience working in the neuromuscular/cardiovascular field is preferred.
  • Hands-on experience with high-content imaging is desirable.
  • Understanding of clinical needs/tractability to guide early programs that will have impact on patient lives is ideal.
  • Ability to work with research vendors and collaborate to manage sponsored research agreements/contracts.
  • Excited to be a part of a multidisciplinary and cross-functional team, but also able to work independently
The Perks

As a Contractor with Entrada, you will be eligible to participate in the Company’s transportation benefit and may expense up to $150 monthly for commuting purposes. Our location in the vibrant and growing Seaport District is close to all the best that the city of Boston has to offer. You will also be able to log Holiday hours to be paid for National Holidays.

Entrada Therapeutics is an equal opportunity employer. Qualified candidates will receive consideration for employment without regard to race, color, religion, national origin, gender, sexual orientation, gender identity or expression, age, mental or physical disability, and genetic information, marital status, citizenship status, military status, protected veteran status or any other category protected by law.

Third Party Staffing Agencies

Entrada does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Entrada from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Entrada and do not obligate Entrada to pay fees if we hire from those resumes.


Entrada Therapeutics is a biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines, Endosomal Escape Vehicle (EEV™) therapeutics, to engage intracellular targets that have long been considered inaccessible and undruggable. The Company’s EEV therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues with an improved therapeutic index. Through its proprietary, highly versatile and modular EEV platform, Entrada is building a robust development portfolio of oligonucleotide-, antibody- and enzyme-based programs for the potential treatment of neuromuscular diseases, immunology, oncology and diseases of the central nervous system. The Company’s lead oligonucleotide programs include ENTR-601-44 targeting Duchenne muscular dystrophy (DMD) and ENTR-701 targeting myotonic dystrophy type 1 (DM1).

Stock Symbol: TRDA
Stock Exchange: NASDAQ



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